IQGAP1 and its binding proteins control diverse biological functions. - Wikidata - wikimedia - TriplyDB

IQGAP1 and its binding proteins control diverse biological functions.

IQGAP1 and its binding proteins control diverse biological functions.

http://www.wikidata.org/entity/Q35713259

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IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.The exocyst at the interface between cytoskeleton and membranes in eukaryotic cells The biology of IQGAP proteins: beyond the cytoskeleton β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1 Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1 Raf-interactome in tuning the complexity and diversity of Raf function.PIP kinases define PI4,5P₂signaling specificity by association with effectors Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model.IQGAP1 mediates angiotensin II-induced apoptosis of podocytes via the ERK1/2 MAPK signaling pathway IQGAP1 links PDGF receptor-β signal to focal adhesions involved in vascular smooth muscle cell migration: role in neointimal formation after vascular injury Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors.IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis.Targeted knockdown of IQGAP1 inhibits the progression of esophageal squamous cell carcinoma in vitro and in vivo.Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy A novel role for IQGAP1 protein in cell motility through cell retraction The coordinating role of IQGAP1 in the regulation of local, endosome-specific actin networks.B-Raf regulation of integrin α4β1-mediated resistance to shear stress through changes in cell spreading and cytoskeletal association in T cells IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM.Dynamic multiprotein assemblies shape the spatial structure of cell signaling An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2.Oligomerization and nanocluster organization render specificity.IQ domain GTPase-activating protein 1 is involved in shear stress-induced progenitor-derived endothelial cell alignment Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier.IQGAPs choreograph cellular signaling from the membrane to the nucleus IQGAP1 regulates actin cytoskeleton organization in podocytes through interaction with nephrin IQGAP3 promotes EGFR-ERK signaling and the growth and metastasis of lung cancer cells.Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.Alkannin inhibits growth and invasion of glioma cells C6 through IQGAP/mTOR signal pathway.IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes IQGAP1 and IQGAP3 Serve Individually Essential Roles in Normal Epidermal Homeostasis and Tumor Progression.Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization.IQGAP1 is associated with nuclear envelope reformation and completion of abscission Identifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network.Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular Carcinoma Reactive oxygen species in vascular formation and development.

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P2860

IQGAP1 and its binding proteins control diverse biological functions.

http://www.wikidata.org/entity/Q35713259

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

IQGAP1 and its binding proteins control diverse biological functions.

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IQGAP1 and its binding proteins control diverse biological functions.

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IQGAP1 and its binding proteins control diverse biological functions.

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IQGAP1 and its binding proteins control diverse biological functions.

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IQGAP1 and its binding proteins control diverse biological functions.

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IQGAP1 and its binding proteins control diverse biological functions.

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J.CELLSIG.2011.12.005

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Cellular Signalling

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IQGAP1 and its binding proteins control diverse biological functions.

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Colin D White

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David B Sacks

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Huseyin H Erdemir

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P2860

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.

MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation

IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line

Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex

IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance

IQGAP1 modulates activation of B-Raf

Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible

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10.1016/J.CELLSIG.2011.12.005

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