Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development - Wikidata - wikimedia - TriplyDB

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

http://www.wikidata.org/entity/Q35723398

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Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor The RNA Splicing Response to DNA Damage Intricate Transcriptional Networks of Classical Brown and Beige Fat Cells EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice.Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo.The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.The D4Z4 macrosatellite repeat acts as a CTCF and A-type lamins-dependent insulator in facio-scapulo-humeral dystrophy.Global survey of protein expression during gonadal sex determination in mice Phenotyping male infertility in the mouse: how to get the most out of a 'non-performer'EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo.FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts.RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.The TET family of proteins: functions and roles in disease.A genetic dichotomy between pure sclerosing epithelioid fibrosarcoma (SEF) and hybrid SEF/low-grade fibromyxoid sarcoma: a pathologic and molecular study of 18 cases Ewing sarcoma gene Ews regulates hematopoietic stem cell senescence.The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage Ewing sarcoma ewsa protein regulates chondrogenesis of Meckel's cartilage through modulation of Sox9 in zebrafish.Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis.Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements Cigarette smoke component acrolein modulates chromatin assembly by inhibiting histone acetylation.EWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing's Sarcoma EWSR1 regulates mitosis by dynamically influencing microtubule acetylation.Loss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish.A multifunctional protein, EWS, is essential for early brown fat lineage determination.A multifunctional protein EWS regulates the expression of Drosha and microRNAs.Efficacy of ATR inhibitors as single agents in Ewing sarcoma.PRDM9 interactions with other proteins provide a link between recombination hotspots and the chromosomal axis in meiosis The spectrum of EWSR1-rearranged neoplasms at a tertiary sarcoma centre; assessing 772 tumour specimens and the value of current ancillary molecular diagnostic modalities.TGF-beta-dependent and -independent roles of STRAP in cancer.Ewing sarcoma protein: a key player in human cancer RNA splicing: a new player in the DNA damage response The diversity of soft tissue tumours with EWSR1 gene rearrangements: a review.RNA-binding proteins as molecular links between cancer and neurodegeneration.Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9.Structure-function based molecular relationships in Ewing's sarcoma.The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability.Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair.

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Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

http://www.wikidata.org/entity/Q35723398

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

@ast

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

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type

label

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

@ast

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

@en

prefLabel

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

@ast

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

@en

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P1433

Journal of Clinical Investigation

P1476

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development

@en

P2093

Alissa Parmelee

http://www.w3.org/2001/XMLSchema#string

Chuxia Deng

http://www.w3.org/2001/XMLSchema#string

Cuiling Li

http://www.w3.org/2001/XMLSchema#string

Hongjie Li

http://www.w3.org/2001/XMLSchema#string

John O'Shea

http://www.w3.org/2001/XMLSchema#string

Mark A Bryant

http://www.w3.org/2001/XMLSchema#string

Sean Bong Lee

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Wendy Watford

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P2860

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation

The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

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1314-1323

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scholarly article

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10.1172/JCI31222

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P433

5

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117

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2007-04-05T00:00:00Z

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6407589

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17415412

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1838927

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