5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint. - Wikidata - wikimedia - TriplyDB

5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.

5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.

http://www.wikidata.org/entity/Q35728207

about

Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1 The position of the amino group on the benzene ring is critical for mesalamine's improvement of replication fidelity.In vivo effects of mesalazine or E. coli Nissle 1917 on microsatellite instability in ulcerative colitis Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells.Overexpression of PAK1 promotes cell survival in inflammatory bowel diseases and colitis-associated cancer.Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice Cost effectiveness of ulcerative colitis surveillance in the setting of 5-aminosalicylates.Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis.Colorectal cancer chemoprevention by mesalazine and its derivatives.Mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDs) and mesalazine in the chemoprevention of colorectal cancer.Chemoprevention of colorectal cancer in inflammatory bowel disease.Systematic review with meta-analysis: use of 5-aminosalicylates and risk of colorectal neoplasia in patients with inflammatory bowel disease.Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study.Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest Mesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.Molecular basis of the potential of mesalazine to prevent colorectal cancer.Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells.5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modes.DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.Identification of PMN-released Mutagenic Factors in a Co-culture Model for Colitis-associated Cancer.5-Aminosalicylic Acid Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats by Increasing the Expression of Nur77.

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P2860

5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint.

http://www.wikidata.org/entity/Q35728207

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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5-ASA affects cell cycle progr ...... ting a replication checkpoint.

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5-ASA affects cell cycle progr ...... ting a replication checkpoint.

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5-ASA affects cell cycle progr ...... ting a replication checkpoint.

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J.GASTRO.2006.10.016

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Gastroenterology

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5-ASA affects cell cycle progr ...... ting a replication checkpoint.

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Christoph Campregher

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Christoph Gasche

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John M Fortune

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M Gloria Luciani

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Thomas A Kunkel

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P2860

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon

Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2

Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex.

Checkpoints: controls that ensure the order of cell cycle events

The DNA damage response: putting checkpoints in perspective

Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease

Mesalazine improves replication fidelity in cultured colorectal cells

A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells

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10.1053/J.GASTRO.2006.10.016

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