Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functions.
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TGF-β: guardian of T cell functionMicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitisTGF-β activation and function in immunity.Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity.A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling.Smad4 promotes differentiation of effector and circulating memory CD8 T cells but is dispensable for tissue-resident memory CD8 T cellsThe kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.A Role for the Non-Canonical Wnt-β-Catenin and TGF-β Signaling Pathways in the Induction of Tolerance during the Establishment of a Salmonella enterica Serovar Enteritidis Persistent Cecal Infection in ChickensTGF-β in tolerance, development and regulation of immunityExcessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasisActivin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in CancerSmad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse.Impact of T-cell-specific Smad4 deficiency on the development of autoimmune diabetes in NOD mice.SMAD regulatory networks construct a balanced immune system.The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases.Foxp3, Regulatory T Cell, and Autoimmune Diseases.Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development.TGF-β1 suppresses CCL3/4 expression through the ERK signaling pathway and inhibits intervertebral disc degeneration and inflammation-related pain in a rat modelCTLA4Ig inhibits effector T cells through regulatory T cells and TGF-β.The aptamer-siRNA conjugates: reprogramming T cells for cancer therapy.TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut.TGF-β1/Smad2/3/Foxp3 signaling is required for chronic stress-induced immune suppression.Transforming growth factor-β signaling in systemic sclerosis.Cytokine mediators of chronic graft-versus-host disease.Functions of Smad Transcription Factors in TGF-β1-Induced Selectin Ligand Expression on Murine CD4 Th Cells.miR-466a Targeting of TGF-β2 Contributes to FoxP3+ Regulatory T Cell Differentiation in a Murine Model of Allogeneic Transplantation.The role of TGF-β in Th17 differentiation.Naringenin Modifies the Development of Lineage-Specific Effector CD4 T Cells
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P2860
Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functions.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Requirements of transcription ...... rol discrete T-cell functions.
@ast
Requirements of transcription ...... rol discrete T-cell functions.
@en
type
label
Requirements of transcription ...... rol discrete T-cell functions.
@ast
Requirements of transcription ...... rol discrete T-cell functions.
@en
prefLabel
Requirements of transcription ...... rol discrete T-cell functions.
@ast
Requirements of transcription ...... rol discrete T-cell functions.
@en
P2093
P2860
P356
P1476
Requirements of transcription ...... trol discrete T-cell functions
@en
P2093
P2860
P304
P356
10.1073/PNAS.1108352109
P407
P50
P577
2012-01-04T00:00:00Z