JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer - Wikidata - wikimedia - TriplyDB

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

http://www.wikidata.org/entity/Q35740107

about

Glucose metabolism in gastric cancer: The cutting-edge Ovarian clear cell carcinoma meets metabolism; HNF-1β confers survival benefits through the Warburg effect and ROS reduction Generating Gene Ontology-Disease Inferences to Explore Mechanisms of Human Disease at the Comparative Toxicogenomics Database Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth.Recent Advances in Targeting Tumor Energy Metabolism with Tumor Acidosis as a Biomarker of Drug Efficacy.The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer HPV E6/p53 mediated down-regulation of miR-34a inhibits Warburg effect through targeting LDHA in cervical cancer.The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma.JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer.Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas.BRD4 promotes gastric cancer progression through the transcriptional and epigenetic regulation of c-MYC.Biological function and histone recognition of family IV bromodomain-containing proteins.Mitochondrial pyruvate carrier function and cancer metabolism.Structural features and inhibitors of bromodomains.Functional Effects of Cigarette Smoke-Induced Changes in Airway Smooth Muscle Mitochondrial Morphology.Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression.Epigenetic pathway inhibitors represent potential drugs for treating pancreatic and bronchial neuroendocrine tumors.BET protein inhibitor JQ1 inhibits growth and modulates WNT signaling in mesenchymal stem cells.Phenformin has anti-tumorigenic effects in human ovarian cancer cells and in an orthotopic mouse model of serous ovarian cancer.The BET inhibitor INCB054329 reduces homologous recombination efficiency and augments PARP inhibitor activity in ovarian cancer.Time-Dependent Effects of POT1 Knockdown on Proliferation, Tumorigenicity, and HDACi Response of SK-OV3 Ovarian Cancer Cells.

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JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

http://www.wikidata.org/entity/Q35740107

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

@zh-cn

name

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

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JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

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type

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JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

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JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

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prefLabel

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

@ast

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

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ONCOTARGET.3126

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JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer

@en

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Amanda L Jackson

http://www.w3.org/2001/XMLSchema#string

Chunxiao Zhou

http://www.w3.org/2001/XMLSchema#string

Haifeng Qiu

http://www.w3.org/2001/XMLSchema#string

Joshua E Kilgore

http://www.w3.org/2001/XMLSchema#string

Leo Li-Ying Chan

http://www.w3.org/2001/XMLSchema#string

Paola A Gehrig

http://www.w3.org/2001/XMLSchema#string

Victoria L Bae-Jump

http://www.w3.org/2001/XMLSchema#string

Yan Zhong

http://www.w3.org/2001/XMLSchema#string

P2860

Hallmarks of Cancer: The Next Generation

Selective inhibition of BET bromodomains

Technologies for deriving primary tumor cells for use in personalized cancer therapy

Cancer statistics, 2014

On the Origin of Cancer Cells

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

Comprehensive genomic profiling of epithelial ovarian cancer by next generation sequencing-based diagnostic assay reveals new routes to targeted therapies

The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry

THE METABOLISM OF TUMORS IN THE BODY

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

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6915-6930

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scholarly article

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10.18632/ONCOTARGET.3126

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9

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6

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2015-03-01T00:00:00Z

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273467078

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25762632

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4466659

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