Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in Leishmania. - Wikidata - wikimedia - TriplyDB

Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in Leishmania.

Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in Leishmania.

http://www.wikidata.org/entity/Q35745876

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Centrins, cell cycle regulation proteins in human malaria parasite Plasmodium falciparum Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasis The calpain inhibitor MDL28170 induces the expression of apoptotic markers in Leishmania amazonensis promastigotes Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins Biomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications.Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family Leishmaniasis Vaccine: Where are We Today?Characterization of a Leishmania stage-specific mitochondrial membrane protein that enhances the activity of cytochrome c oxidase and its role in virulence Visceral Leishmaniasis: Advancements in Vaccine Development via Classical and Molecular Approaches Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex.Role of centrins 2 and 3 in organelle segregation and cytokinesis in Trypanosoma brucei Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 in Leishmania donovani results in loss of β-oxidation of fatty acids and blocks cell division in the amastigote stage.Calcium signaling in trypanosomatid parasites Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection.Genetically Modified Live Attenuated Leishmania donovani Parasites Induce Innate Immunity through Classical Activation of Macrophages That Direct the Th1 Response in Mice.Live Attenuated Leishmania donovani Centrin Knock Out Parasites Generate Non-inferior Protective Immune Response in Aged Mice against Visceral Leishmaniasis.An Sfi1p-like centrin-binding protein mediates centrin-based Ca2+ -dependent contractility in Paramecium tetraurelia Development of Leishmania vaccines: predicting the future from past and present experience.Transgenic Leishmania and the immune response to infection Basal body assembly in ciliates: the power of numbers.Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death.Such small hands: the roles of centrins/caltractins in the centriole and in genome maintenance.Gene-deleted live-attenuated Trypanosoma cruzi parasites as vaccines to protect against Chagas disease.Immunity to visceral leishmaniasis using genetically defined live-attenuated parasites.Leishmaniasis and various immunotherapeutic approaches.Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs.Comparative Proteomic Profiling of Leishmania tropica: Investigation of a Case Infected with Simultaneous Cutaneous and Viscerotropic Leishmaniasis by 2-Dimentional Electrophoresis and Mass Spectrometry.Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization.Centrin1 is required for organelle segregation and cytokinesis in Trypanosoma brucei.Role of Mast Cells in clearance of Leishmania through extracellular trap formation.A twinfilin-like protein coordinates karyokinesis by influencing mitotic spindle elongation and DNA replication in Leishmania.An interplay between Centrin2 and Centrin4 on the bi-lobed structure in Trypanosoma brucei.Immunization with Live Attenuated Leishmania donovani Centrin-/- Parasites Is Efficacious in Asymptomatic Infection.An actin-like protein is involved in regulation of mitochondrial and flagellar functions as well as in intramacrophage survival of Leishmania donovani.Centrin-Deleted Leishmania donovani Parasites Help CD4+ T Cells to Acquire Th1 Phenotype and Multi-Functionality Through Downregulation of CD200-CD200R Immune Inhibitory Axis.Membrane Proteins in Trypanosomatids Involved in Ca2+ Homeostasis and Signaling.Leishmania vaccines: from leishmanization to the era of DNA technology Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice

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P2860

Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in Leishmania.

http://www.wikidata.org/entity/Q35745876

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Centrin gene disruption impair ...... cle progression in Leishmania.

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Centrin gene disruption impair ...... cle progression in Leishmania.

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type

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Centrin gene disruption impair ...... cle progression in Leishmania.

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Centrin gene disruption impair ...... cle progression in Leishmania.

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Centrin gene disruption impair ...... cle progression in Leishmania.

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Centrin gene disruption impair ...... cle progression in Leishmania.

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Journal of Biological Chemistry

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Centrin gene disruption impair ...... cle progression in Leishmania.

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Alain Debrabant

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Angamuthu Selvapandiyan

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Gannavaram Sreenivas

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Hira L Nakhasi

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Jacqueline Muller

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Jeffrey L Salisbury

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Robert Duncan

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P2860

Centrin-2 is required for centriole duplication in mammalian cells

Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication

Centrin4p, a novel mammalian centrin specifically expressed in ciliated cells

Cell death: critical control points

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

Centrin, centrosomes, and mitotic spindle poles

Centrosome-dependent exit of cytokinesis in animal cells.

Development of a safe live Leishmania vaccine line by gene replacement.

Leishmaniasis: current status of vaccine development

Centrosomes: Sfi1p and centrin unravel a structural riddle.

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25703-25710

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10.1074/JBC.M402794200

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24

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279

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15084606

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