An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis
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Fuchs endothelial corneal dystrophy: current perspectivesDepletion of SLC4A11 causes cell death by apoptosis in an immortalized human corneal endothelial cell line.N-Acetylcysteine increases corneal endothelial cell survival in a mouse model of Fuchs endothelial corneal dystrophyDiffering roles for TCF4 and COL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy.A common trinucleotide repeat expansion within the transcription factor 4 (TCF4, E2-2) gene predicts Fuchs corneal dystrophy.Translational models of ocular disease.On the origin of 'guttae'Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals.Endoplasmic Reticulum Stress and Unfolded Protein Response Pathways: Potential for Treating Age-related Retinal DegenerationScreening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative StressEndothelial Cdkn1a (p21) overexpression and accelerated senescence in a mouse model of Fuchs endothelial corneal dystrophyTissue microarray analysis of cyclin-dependent kinase inhibitors p21 and p16 in Fuchs dystrophyKeratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells.Endothelial cell whole genome expression analysis in a mouse model of early-onset Fuchs' endothelial corneal dystrophy.L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy.High osmotic pressure increases reactive oxygen species generation in rabbit corneal epithelial cells by endoplasmic reticulum.In Vivo Imaging of Corneal Endothelial Dystrophy in Boston Terriers: A Spontaneous, Canine Model for Fuchs' Endothelial Corneal Dystrophy.Lithium treatment increases endothelial cell survival and autophagy in a mouse model of Fuchs endothelial corneal dystrophy.Association and familial segregation of CTG18.1 trinucleotide repeat expansion of TCF4 gene in Fuchs' endothelial corneal dystrophy.Endothelial cell microRNA expression in human late-onset Fuchs' dystrophy.Fuchs endothelial cornea dystrophy: a review of the genetics behind disease development.Gender specific issues in hereditary ocular disorders.All-trans retinoic acid protects hepatocellular carcinoma cells against serum-starvation-induced cell death by upregulating collagen 8A2.Collagens and proteoglycans of the cornea: importance in transparency and visual disorders.MicroRNA-29b Overexpression Decreases Extracellular Matrix mRNA and Protein Production in Human Corneal Endothelial Cells.Biomechanical relationships between the corneal endothelium and Descemet's membrane.Loss of ion transporters and increased unfolded protein response in Fuchs' dystrophy.Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model.Transplantation of Human Corneal Endothelial Cells Cultured on Bio-Engineered Collagen Vitrigel in a Rabbit Model of Corneal Endothelial Dysfunction.Perspective of Future Potent Therapies for Fuchs Endothelial Corneal DystrophyLoss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
P2860
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P2860
An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@ast
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@en
type
label
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@ast
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@en
prefLabel
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@ast
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@en
P2093
P2860
P356
P1476
An alpha 2 collagen VIII trans ...... protein response and apoptosis
@en
P2093
Albert S Jun
Mario Matthaei
Martha Kimos
Naren Ramanan
Rhonda Grebe
Richard Bonshek
Shukti Chakravarti
P2860
P304
P356
10.1093/HMG/DDR473
P50
P577
2011-10-14T00:00:00Z