Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update.
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Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide componentIn vivo optical imaging of human vaginal gel thickness distributions with a probe-based, dual-modality instrument.Development of topical microbicides to prevent the sexual transmission of HIVFormulation development and evaluation of innovative two-polymer (SR-2P) bioadhesive vaginal gel.Safety and anti-HIV assessments of natural vaginal cleansing products in an established topical microbicides in vitro testing algorithm.Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.Effectiveness of female controlled barrier methods in preventing sexually transmitted infections and HIV: current evidence and future research directions.Use of human mucosal tissue to study HIV-1 pathogenesis and evaluate HIV-1 prevention modalities.Rectal microbicide development.In vitro microbicidal activity of the nonnucleoside reverse transcriptase inhibitor (NNRTI) UC781 against NNRTI-resistant human immunodeficiency virus type 1Topical microbicides to prevent the transmission of HIV: formulation gaps and challengesDynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory.Enzymatic triggered release of an HIV-1 entry inhibitor from prostate specific antigen degradable microparticles.Evaluation of Cynanchum otophyllum glucan sulfate against human immunodeficiency virus and herpes simplex virus as a microbicide agent.Novel vaginal microflora colonization model providing new insight into microbicide mechanism of action.The sheep as a model of preclinical safety and pharmacokinetic evaluations of candidate microbicidesThe Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets.Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity.Comparative evaluation of virus transmission inhibition by dual-acting pyrimidinedione microbicides using the microbicide transmission and sterilization assayToll-like receptors and cytokines as surrogate biomarkers for evaluating vaginal immune response following microbicide administration.Mucosal immunity to HIV: a review of recent literature.Vaginal drug delivery systems for HIV prevention.Second-generation HIV microbicides: continued development of griffithsin.A model of transluminal flow of an anti-HIV microbicide vehicle: Combined elastic squeezing and gravitational sliding.The second wave: Toward responsible inclusion of pregnant women in researchMicrobicidas Metodo de Prevencion en VIH/SIDA Controlado por MujeresPharmaceutical development of microbicide drug products.Current and future microbicide approaches aimed at preventing HIV infection in women.Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis.Evaluation of immunological markers of ovine vaginal irritation: Implications for preclinical assessment of non-vaccine HIV preventive agents.Biomarkers of leukocyte traffic and activation in the vaginal mucosa.Vaginal Mucosa and Drug Delivery
P2860
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P2860
Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Recommendations for the noncli ...... f HIV transmission: an update.
@ast
Recommendations for the noncli ...... f HIV transmission: an update.
@en
type
label
Recommendations for the noncli ...... f HIV transmission: an update.
@ast
Recommendations for the noncli ...... f HIV transmission: an update.
@en
prefLabel
Recommendations for the noncli ...... f HIV transmission: an update.
@ast
Recommendations for the noncli ...... f HIV transmission: an update.
@en
P2093
P1476
Recommendations for the noncli ...... f HIV transmission: an update.
@en
P2093
Charles Litterst
Dorota Matecka
International Working Group on Microbicides
Ita S Yuen
Julian J O'Rear
Patricia Reichelderfer
Sheryl L Lard-Whiteford
P304
P356
10.1097/00126334-200405010-00001
P407
P577
2004-05-01T00:00:00Z