Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis - Wikidata - wikimedia - TriplyDB

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

http://www.wikidata.org/entity/Q35752661

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Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies A candidate gene study of CLEC16A does not provide evidence of association with risk for anti-CCP-positive rheumatoid arthritis Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: A systematic review and meta-analysis Chronic inflammatory systemic diseases: An evolutionary trade-off between acutely beneficial but chronically harmful programs Relationship between Periodontitis and Rheumatoid Arthritis: Review of the Literature Environmental risk factors for multiple sclerosis: a review with a focus on molecular mechanisms The effect of targeted rheumatoid arthritis therapies on anti-citrullinated protein autoantibody levels and B cell responses The lung in ACPA-positive rheumatoid arthritis: an initiating site of injury?Epidemiology of environmental exposures and human autoimmune diseases: findings from a National Institute of Environmental Health Sciences Expert Panel Workshop The Effect of Stopping Smoking on Disease Activity in Rheumatoid Arthritis (RA). Data from BARFOT, a Multicenter Study of Early RA A replication study confirms the association of dendritic cell immunoreceptor (DCIR) polymorphisms with ACPA - negative RA in a large Asian cohort A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis Mutual information for testing gene-environment interaction.An African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans.A combinatorial approach for detecting gene-gene interaction using multiple traits of Genetic Analysis Workshop 16 rheumatoid arthritis data.Detecting single-nucleotide polymorphism by single-nucleotide polymorphism interactions in rheumatoid arthritis using a two-step approach with machine learning and a Bayesian threshold least absolute shrinkage and selection operator (LASSO) model Allelic based gene-gene interactions in rheumatoid arthritis.Identification of gene-gene interaction using principal components PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs Detecting Genes and Gene-gene Interactions for Age-related Macular Degeneration with a Forest-based Approach Validation of Leiden Score in Predicting Progression of Rheumatoid Arthritis in Undifferentiated Arthritis in Indian Population.Global metabolite profiling of synovial fluid for the specific diagnosis of rheumatoid arthritis from other inflammatory arthritis.Gene-gene and gene-environment interactions in ulcerative colitis.Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases.Gene- or region-based association study via kernel principal component analysis.PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis.Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis.Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis A nonparametric regression method for multiple longitudinal phenotypes using multivariate adaptive splines Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis.Interaction between smoking and HLA-DRB1*04 gene is associated with a high cardiovascular risk in Brazilian Amazon patients with rheumatoid arthritis.Socioeconomic disparities in the health of african americans with rheumatoid arthritis from the southeastern United States.Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case-control study.Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.Interleukin-27 and interferon-gamma are involved in regulation of autoimmune arthritis

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P2860

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

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Gene-gene and gene-environment ...... ubsets of rheumatoid arthritis

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Gene-gene and gene-environment ...... ubsets of rheumatoid arthritis

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Gene-gene and gene-environment ...... ubsets of rheumatoid arthritis

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Gene-gene and gene-environment ...... ubsets of rheumatoid arthritis

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P2093

Epidemiological Investigation of Rheumatoid Arthritis study group

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Henrik Kallberg

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Johan Ronnelid

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Robert M Plenge

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Tom W Huizinga

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P2860

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity

The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status.

A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis.

Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases.

Test for interaction between two unlinked loci.

Socioeconomic status and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study.

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Lars Alfredsson

Leonid Padyukov

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Peter K. Gregersen

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