The relevance of iron in the pathogenesis of Parkinson's disease.
about
Proteome analysis of human substantia nigra in Parkinson's diseaseTowards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesParkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicityFerritin for the clinicianIron homeostasis in neuronal cells: a role for IREG1Catecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disordersRegulation of brain iron and copper homeostasis by brain barrier systems: implication in neurodegenerative diseasesCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesEffects of opiates and HIV proteins on neurons: the role of ferritin heavy chain and a potential for synergismProgressive supranuclear palsy: high-field-strength MR microscopy in the human substantia nigra and globus pallidus.A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools.Iron contributes to the formation of catechol isoquinolines and oxidative toxicity induced by overdose dopamine in dopaminergic SH-SY5Y cells.The viral protein Egf1.0 is a dual activity inhibitor of prophenoloxidase-activating proteinases 1 and 3 from Manduca sexta.Caenorhabditis elegans: a model to investigate oxidative stress and metal dyshomeostasis in Parkinson's diseaseBrain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson's disease.Conjugal Parkinsonism and Parkinson disease: a case series with environmental risk factor analysis.MRI T2 Hypointensities in basal ganglia of premanifest Huntington's diseasePathogenic implications of iron accumulation in multiple sclerosis.Eryptosis as a marker of Parkinson's diseaseA novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease.Accumulation of nuclear DNA damage or neuron loss: molecular basis for a new approach to understanding selective neuronal vulnerability in neurodegenerative diseases.Oxidative stress in neurodegenerationPotential of Diffusion Tensor Imaging and Relaxometry for the Detection of Specific Pathological Alterations in Parkinson's Disease (PD)Chelators in the treatment of iron accumulation in Parkinson's disease.Metal transporters in intestine and brain: their involvement in metal-associated neurotoxicities.Genetics of iron regulation and the possible role of iron in Parkinson's disease.GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein.Glutathione metabolism and Parkinson's disease.Copper(II) binding to alpha-synuclein, the Parkinson's protein.Inhibition of the Fe(III)-catalyzed dopamine oxidation by ATP and its relevance to oxidative stress in Parkinson's diseaseThe power plant of the cell is also a smithy: the emerging role of mitochondria in cellular iron homeostasis.Activation of ATP-sensitive potassium channels enhances DMT1-mediated iron uptake in SK-N-SH cells in vitro.Targeting the progression of Parkinson's disease.Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson's disease in Indian population.Low levels of arsenite activates nuclear factor-kappaB and activator protein-1 in immortalized mesencephalic cells.Iron Chelators as Potential Therapeutic Agents for Parkinson's DiseaseMotor phenotype and magnetic resonance measures of basal ganglia iron levels in Parkinson's disease.Profound morphological changes in the erythrocytes and fibrin networks of patients with hemochromatosis or with hyperferritinemia, and their normalization by iron chelators and other agents.Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels.
P2860
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P2860
The relevance of iron in the pathogenesis of Parkinson's disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The relevance of iron in the pathogenesis of Parkinson's disease.
@ast
The relevance of iron in the pathogenesis of Parkinson's disease.
@en
type
label
The relevance of iron in the pathogenesis of Parkinson's disease.
@ast
The relevance of iron in the pathogenesis of Parkinson's disease.
@en
prefLabel
The relevance of iron in the pathogenesis of Parkinson's disease.
@ast
The relevance of iron in the pathogenesis of Parkinson's disease.
@en
P2093
P2860
P356
P1476
The relevance of iron in the pathogenesis of Parkinson's disease
@en
P2093
Manfred Gerlach
Mario E Götz
Moussa B H Youdim
Peter Riederer
P2860
P304
P356
10.1196/ANNALS.1306.017
P407
P50
P577
2004-03-01T00:00:00Z