Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo
about
Hereditary alpha-1-antitrypsin deficiency and its clinical consequencesRationale and design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis. Alpha-1 protocolGenes and chronic obstructive pulmonary diseaseα-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8Alpha-1-antitrypsin deficiencyDiscovery of an inhibitor of Z-alpha1 antitrypsin polymerizationZ α1-antitrypsin confers a proinflammatory phenotype that contributes to chronic obstructive pulmonary diseaseThe role of bronchial epithelial cells in the pathogenesis of COPD in Z-alpha-1 antitrypsin deficiencyProtein misfolding and the serpinopathies.Therapy with plasma purified alpha1-antitrypsin (Prolastin®) induces time-dependent changes in plasma levels of MMP-9 and MPO.ATZ11 recognizes not only Z-α1-antitrypsin-polymers and complexed forms of non-Z-α1-antitrypsin but also the von Willebrand factor.Therapeutic targeting of misfolding and conformational change in α1-antitrypsin deficiency.Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesisRandomised controlled crossover trial of humidified continuous positive airway pressure in mild obstructive sleep apnoeaNeutrophilic inflammation and IL-8 levels in induced sputum of alpha-1-antitrypsin PiMZ subjectsThe effects of weekly augmentation therapy in patients with PiZZ α1-antitrypsin deficiency.The selective advantage of alpha1-antitrypsin deficiency.Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.Role of lung maintenance program in the heterogeneity of lung destruction in emphysema.Alpha-1-antitrypsin deficiency: current concepts.Multilineage transduction of resident lung cells in vivo by AAV2/8 for α1-antitrypsin gene therapy.Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease.Polymers and inflammation: disease mechanisms of the serpinopathiesSafety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.Intracellular and extracellular serpins modulate lung disease.Oxidized {alpha}1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.New Findings in PiZZ alpha1-antitrypsin deficiency-related panniculitis. Demonstration of skin polymers and high dosing requirements of intravenous augmentation therapy.alpha1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies.Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies.Lung disease associated with alpha1-antitrypsin deficiency.Hepatic fibrosis and carcinogenesis in α1-antitrypsin deficiency: a prototype for chronic tissue damage in gain-of-function disorders.α(1)-antitrypsin deficiency and inflammation.The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and α-1 anti-trypsin deficiency.Twenty years of polymers: a personal perspective on alpha-1 antitrypsin deficiency.Airway disease in alpha-1 antitrypsin deficiency.Recent advances in α-1-antitrypsin deficiency-related lung disease.Alpha-1-antitrypsin deficiency: increasing awareness and improving diagnosis.Neutrophilic panniculitis associated with alpha-1-antitrypsin deficiency: an update.Risk of Lung Disease in PI MZ Heterozygotes. Current Status and Future Research Directions.
P2860
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P2860
Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@ast
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@en
type
label
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@ast
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@en
prefLabel
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@ast
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@en
P2093
P2860
P1476
Polymers of Z alpha1-antitryps ...... li and are chemotactic in vivo
@en
P2093
Carl Atkinson
David A Lomas
Diane G Kelley
Jasvir Parmar
Ravi Mahadeva
Rebecca Pitman
Steven D Shapiro
Susan Stewart
Zhenjun Li
P2860
P304
P356
10.1016/S0002-9440(10)62261-4
P407
P577
2005-02-01T00:00:00Z