L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia.
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Advances in Autophagy Regulatory MechanismsSLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanismsGenetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population.Leucine Metabolism in T Cell Activation: mTOR Signaling and Beyond.Aryl hydrocarbon receptor (AHR) regulation of L-Type Amino Acid Transporter 1 (LAT-1) expression in MCF-7 and MDA-MB-231 breast cancer cellsSpecific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging.LAT-1 activity of meta-substituted phenylalanine and tyrosine analogsDeletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer CellsMYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4.ASCT2 regulates glutamine uptake and cell growth in endometrial carcinomaGlutamine transporters in mammalian cells and their functions in physiology and cancer.Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment.Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy.Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters.LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substratesFTY720-induced endocytosis of yeast and human amino acid transporters is preceded by reduction of their inherent activity and TORC1 inhibition.Characterisation of L-Type Amino Acid Transporter 1 (LAT1) Expression in Human Skeletal Muscle by Immunofluorescent Microscopy.Role of SLC7A5 in Metabolic Reprogramming of Human Monocyte/Macrophage Immune Responses.Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1.The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours.Supplementation of branched-chain amino acids in protein-restricted diets modulates the expression levels of amino acid transporters and energy metabolism associated regulators in the adipose tissue of growing pigs.Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration.Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways.Hepatitis C Virus Modulates Solute carrier family 3 member 2 for Viral PropagationThe LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse modelThe Regulation and Function of the L-Type Amino Acid Transporter 1 (LAT1) in CancerLAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer
P2860
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P2860
L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia.
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
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2015年论文
@zh-cn
name
L-type amino acid transport an ...... pathway to inhibit neoplasia.
@ast
L-type amino acid transport an ...... pathway to inhibit neoplasia.
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type
label
L-type amino acid transport an ...... pathway to inhibit neoplasia.
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L-type amino acid transport an ...... pathway to inhibit neoplasia.
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prefLabel
L-type amino acid transport an ...... pathway to inhibit neoplasia.
@ast
L-type amino acid transport an ...... pathway to inhibit neoplasia.
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P2860
P1476
L-type amino acid transport an ...... pathway to inhibit neoplasia.
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P2093
P2860
P304
P577
2015-03-15T00:00:00Z