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Quorum quenching quandary: resistance to antivirulence compounds

Quorum quenching quandary: resistance to antivirulence compounds

http://www.wikidata.org/entity/Q35758927

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Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation Bygiene: The New Paradigm of Bidirectional Hygiene Genetic control of bacterial biofilms Role of quorum sensing in bacterial infections Collective sensing and collective responses in quorum-sensing bacteria Quorum quenching revisited--from signal decays to signalling confusion Resistance to quorum-quenching compounds Subtilase SprP exerts pleiotropic effects in Pseudomonas aeruginosa Multiple-omic data analysis of Klebsiella pneumoniae MGH 78578 reveals its transcriptional architecture and regulatory features Escherichia coli resistance to nonbiocidal antibiofilm polysaccharides is rare and mediated by multiple mutations leading to surface physicochemical modifications In Silico Evaluation of the Impacts of Quorum Sensing Inhibition (QSI) on Strain Competition and Development of QSI Resistance Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation Quorum quenching agents: resources for antivirulence therapy Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria Antibiotic adjuvants: diverse strategies for controlling drug-resistant pathogens.Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target.Interactions among quorum sensing inhibitors.Quorum sensing enhancement of the stress response promotes resistance to quorum quenching and prevents social cheating.Antivirulence therapy for animal production: filling an arsenal with novel weapons for sustainable disease control.Targeting virulence not viability in the search for future antibacterials.Genes as early responders regulate quorum-sensing and control bacterial cooperation in Pseudomonas aeruginosa.Drug repurposing as an alternative for the treatment of recalcitrant bacterial infections.Synthesis and biological evaluation of novel N-α-haloacylated homoserine lactones as quorum sensing modulators Molecular basis of in vivo biofilm formation by bacterial pathogens Exploiting quorum sensing to confuse bacterial pathogens.Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?Selection of the N-Acylhomoserine Lactone-Degrading Bacterium Alteromonas stellipolaris PQQ-42 and of Its Potential for Biocontrol in Aquaculture.Plant-derived natural products as sources of anti-quorum sensing compounds.Small-molecule inhibitors of toxT expression in Vibrio cholerae.Is Quorum Sensing Interference a Viable Alternative to Treat Pseudomonas aeruginosa Infections?Halogenated indoles eradicate bacterial persister cells and biofilms.Manipulating virulence factor availability can have complex consequences for infections.Gallium-mediated siderophore quenching as an evolutionarily robust antibacterial treatment.Effect of Quorum Quenching Lactonase in Clinical Isolates of Pseudomonas aeruginosa and Comparison with Quorum Sensing Inhibitors.Microbial Biofilms and Chronic Wounds Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors.Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials.Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.

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P2860

Quorum quenching quandary: resistance to antivirulence compounds

http://www.wikidata.org/entity/Q35758927

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The ISME Journal

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Quorum quenching quandary: resistance to antivirulence compounds

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Lili Sheng

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Luis Rene Garcia

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Maria Tomás

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Mingming Pu

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Rodolfo García-Contreras

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Thomas K Wood

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Toshinari Maeda

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P2860

The genetics of Caenorhabditis elegans

Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals

Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR

Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model

Quorum-sensing-negative (lasR) mutants of Pseudomonas aeruginosa avoid cell lysis and death

Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885)

BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14.

An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants

Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment

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493-501

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10.1038/ISMEJ.2011.122

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21918575

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3280137

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