Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans
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Adverse effects of pefloxacin in irradiated C3H/HeN mice: correction with glucan therapyUse of fluoroquinolones for prophylaxis of murine Pneumocystis carinii pneumoniaPharmacokinetics of pefloxacin and its interaction with cyclosporin A, a P-glycoprotein modulator, in rat blood, brain and bile, using simultaneous microdialysisEfficacy of pefloxacin-fosfomycin in experimental endocarditis caused by methicillin-resistant Staphylococcus aureusActivity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse modelChemotherapeuticsEvaluation of quinolones in experimental animal models of infections.Characterization of a new norfloxacin metabolite monitored during a bioequivalence study by means of mass spectrometry and quantum computation.Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens.Determination of pefloxacin concentration in mesenteric lymph nodes by high-performance chromatography.Proteoglycan and collagen biochemical variations during fluoroquinolone-induced chondrotoxicity in micePefloxacin-induced achilles tendon toxicity in rodents: biochemical changes in proteoglycan synthesis and oxidative damage to collagen.Randomized, double-blind comparison of single-dose regimens of rufloxacin and pefloxacin for acute uncomplicated cystitis in women. French Multicenter Urinary Tract Infection-Rufloxacin GroupPenetration of pefloxacin into bronchial secretionsActivities of pefloxacin and ciprofloxacin against experimental malaria in mice.Pharmacokinetics and biliary concentrations of fleroxacin in cholecystectomized patientsHepatobiliary kinetics and excretion of ciprofloxacin.Recovery of pefloxacin in saliva and feces and its action on oral and fecal floras of healthy volunteers.Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis.The fluoroquinolones: pharmacology, clinical uses, and toxicities in humans.In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones.Bactericidal activity and killing rate of serum from volunteers receiving pefloxacin alone or in combination with amikacin.Metabolism and disposition of amifloxacin in laboratory animalsPharmacokinetics of a new quinolone, AM-833, in mice, rats, rabbits, dogs, and monkeysPharmacokinetics and bactericidal activities of one 800-milligram dose versus two 400-milligram doses of intravenously administered pefloxacin in healthy volunteers.Pharmacokinetic studies of CP-74,667, a new quinolone, in laboratory animals.Ciprofloxacin biliary disposition in cholecystectomised patients with special references to HPLC and bioassay data.Prediction of brain delivery of ofloxacin, a new quinolone, in the human from animal data.Pharmacokinetics of temafloxacin in humans after single oral doses.Tentative disk diffusion susceptibility interpretive criteria for pefloxacinPharmacokinetics of quinolones: newer aspects.Potential role of fluoroquinolones in the treatment of bacterial meningitis.Physiologically based pharmacokinetic tissue compartment model selection in drug development and risk assessmentThe 4-quinolone antibiotics: past, present, and future.Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats.The quinolones: an overview and comparative appraisal of their pharmacokinetics and pharmacodynamics.Fluorinated quinolones. A review of their mode of action, antimicrobial activity, pharmacokinetics and clinical efficacy.Characterization of fluoroquinolone-induced Achilles tendon toxicity in rats: comparison of toxicities of 10 fluoroquinolones and effects of anti-inflammatory compounds.Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone.Difloxacin metabolism and pharmacokinetics in humans after single oral doses
P2860
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P2860
Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
@ast
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
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type
label
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
@ast
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
@en
prefLabel
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
@ast
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
@en
P2093
P2860
P356
P1476
Absorption, distribution, meta ...... ats, dogs, monkeys, and humans
@en
P2093
P2860
P304
P356
10.1128/AAC.25.4.463
P407
P577
1984-04-01T00:00:00Z