Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity
about
Silent Polymorphisms: Can the tRNA Population Explain Changes in Protein Properties?The Epitranscriptome and Innate ImmunityModification of the wobble uridine in bacterial and mitochondrial tRNAs reading NNA/NNG triplets of 2-codon boxesRNA mediated Toll-like receptor stimulation in health and diseaseMethylated nucleosides in tRNA and tRNA methyltransferasesDistribution and frequencies of post-transcriptional modifications in tRNAs.MODOMICS: a database of RNA modification pathways--2013 updateThe catalytic domain of topological knot tRNA methyltransferase (TrmH) discriminates between substrate tRNA and nonsubstrate tRNA via an induced-fit process.Transfer RNA and human diseaseUnderstanding RNA modifications: the promises and technological bottlenecks of the 'epitranscriptome'.Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR.Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2Substrate tRNA recognition mechanism of eubacterial tRNA (m1A58) methyltransferase (TrmI).A single naturally occurring 2'-O-methylation converts a TLR7- and TLR8-activating RNA into a TLR8-specific ligandThe RNA-editing enzyme ADAR1 controls innate immune responses to RNA.Bacterial transfer RNAs.Illumina-based RiboMethSeq approach for mapping of 2'-O-Me residues in RNA.Identification of determinants for tRNA substrate recognition by Escherichia coli C/U34 2'-O-methyltransferase.Activation of autoreactive B cells by endogenous TLR7 and TLR3 RNA ligands.Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism.RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection.Microbial recognition and evasion of host immunity.Mass spectrometry analysis of nucleosides and nucleotides.Sensing microbial RNA in the cytosol.Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA.Identification of an optimized 2'-O-methylated trinucleotide RNA motif inhibiting Toll-like receptors 7 and 8.Transfer RNA methyltransferases with a SpoU-TrmD (SPOUT) fold and their modified nucleosides in tRNA.From bacterial to human dihydrouridine synthase: automated structure determination.Small RNA Modifications: Integral to Function and Disease.Discrimination of Self and Non-Self Ribonucleic Acids.Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7.Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2'-O-Methylation.TLR7 inhibition: A novel strategy for pancreatic cancer treatment?Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2.A modified dinucleotide motif specifies tRNA recognition by TLR7.Dye label interference with RNA modification reveals 5-fluorouridine as non-covalent inhibitor.TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6.Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases.tRNA modifications: Necessary for correct tRNA-derived fragments during the recovery from stress?
P2860
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P2860
Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Identification of modification ...... ess immunostimulatory activity
@ast
Identification of modification ...... ess immunostimulatory activity
@en
type
label
Identification of modification ...... ess immunostimulatory activity
@ast
Identification of modification ...... ess immunostimulatory activity
@en
prefLabel
Identification of modification ...... ess immunostimulatory activity
@ast
Identification of modification ...... ess immunostimulatory activity
@en
P2093
P2860
P356
P1476
Identification of modification ...... ess immunostimulatory activity
@en
P2093
Alexander H Dalpke
Flavia Botschen
Florian Eberle
Guillaume Bec
Gérard Keith
Katharina Rimbach
Mariel-Esther Eberle
Mathias Sprinzl
Stefanie Gehrig
Steffen Kaiser
P2860
P304
P356
10.1084/JEM.20111044
P407
P50
P577
2012-02-06T00:00:00Z