The association between sterilizing activity and drug distribution into tuberculosis lesions.
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The emerging role of gasotransmitters in the pathogenesis of tuberculosisNew agents for the treatment of drug-resistant Mycobacterium tuberculosisEssential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosisA Dormant Microbial Component in the Development of PreeclampsiaPediatric multidrug-resistant tuberculosis clinical trials: challenges and opportunitiesCurrent strategies to treat tuberculosisAssessment of treatment response in tuberculosisDriving the Way to Tuberculosis Elimination: The Essential Role of Fundamental ResearchA new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)Challenges in the clinical assessment of novel tuberculosis drugs.A Combination Regimen Design Program Based on Pharmacodynamic Target Setting for Childhood Tuberculosis: Design Rules for the Playground.Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment durationThe within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy.Concentration-Dependent Antagonism and Culture Conversion in Pulmonary Tuberculosis.Importance of Drug Pharmacokinetics at the Site of ActionFragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays.Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis.Inflammatory signaling in human tuberculosis granulomas is spatially organized.Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy.The biodistribution of 5-[18F]fluoropyrazinamide in Mycobacterium tuberculosis-infected mice determined by positron emission tomographyThe top-cited systematic reviews/meta-analyses in tuberculosis research: A PRISMA-compliant systematic literature review and bibliometric analysis.Synthesis and evaluation of pretomanid (PA-824) oxazolidinone hybrids.Are the Present Doses of Anti Tubercular Drugs Adequate for Severe Disease?Selective Inactivity of Pyrazinamide against Tuberculosis in C3HeB/FeJ Mice Is Best Explained by Neutral pH of CaseumBoromycin Kills Mycobacterial Persisters without Detectable ResistanceImmune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo.Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice.High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis.Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9.Temporal and intrinsic factors of rifampicin tolerance in mycobacteria.Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis RegimenStatin adjunctive therapy shortens the duration of TB treatment in mice.Prediction of Drug Penetration in Tuberculosis LesionsThe antifibrotic drug pirfenidone promotes pulmonary cavitation and drug resistance in a mouse model of chronic tuberculosis.Bioluminescent Reporters for Rapid Mechanism of Action Assessment in Tuberculosis Drug Discovery.High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.A temporal proteome dynamics study reveals the molecular basis of induced phenotypic resistance in Mycobacterium smegmatis at sub-lethal rifampicin concentrationsChemical activation of adenylyl cyclase Rv1625c inhibits growth of Mycobacterium tuberculosis on cholesterol and modulates intramacrophage signaling.Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.
P2860
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P2860
The association between sterilizing activity and drug distribution into tuberculosis lesions.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The association between steril ...... ion into tuberculosis lesions.
@ast
The association between steril ...... ion into tuberculosis lesions.
@en
type
label
The association between steril ...... ion into tuberculosis lesions.
@ast
The association between steril ...... ion into tuberculosis lesions.
@en
prefLabel
The association between steril ...... ion into tuberculosis lesions.
@ast
The association between steril ...... ion into tuberculosis lesions.
@en
P2093
P2860
P356
P1433
P1476
The association between steril ...... ion into tuberculosis lesions.
@en
P2093
Brendan Prideaux
Danielle M Weiner
Firat Kaya
Jansy Sarathy
Jeong Su Cho
Kenneth N Olivier
Laura E Via
Matthew D Zimmerman
Myungsun Lee
P2860
P2888
P304
P356
10.1038/NM.3937
P407
P577
2015-09-07T00:00:00Z
P5875
P6179
1039131202