Reversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at puberty
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Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models.Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C diseaseNeurosteroid regulation of central nervous system developmentThe role of ovarian hormone-derived neurosteroids on the regulation of GABAA receptors in affective disordersAllopregnanolone as a mediator of affective switching in reproductive mood disordersChanging neuroestrogens within the auditory forebrain rapidly transform stimulus selectivity in a downstream sensorimotor nucleusCorticotropin-releasing factor modulation of forebrain GABAergic transmission has a pivotal role in the expression of anabolic steroid-induced anxiety in the female mouse.A stress steroid triggers anxiety via increased expression of α4βδ GABAA receptors in methamphetamine dependence.The influence of stress at puberty on mood and learning: role of the α4βδ GABAA receptorEstrous cycle variations in GABA(A) receptor phosphorylation enable rapid modulation by anabolic androgenic steroids in the medial preoptic area.The GABAergic deficit hypothesis of major depressive disorder.Neurosteroid influences on sensitivity to ethanolA neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder.Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits.Why do many psychiatric disorders emerge during adolescence?Withdrawal from THC during adolescence: sex differences in locomotor activity and anxiety.Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressantsSimultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Attenuates Cerebral Ischemia Injury In Vivo and Vitro by Differential Modulations of NMDA Receptors Subunit Components at Different Post-Ischemia Stage in MiceDifferential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.Excitatory synapses on dendritic shafts of the caudal basal amygdala exhibit elevated levels of GABAA receptor α4 subunits following the induction of activity-based anorexia.Postdepolarization potentiation of GABAA receptors: a novel mechanism regulating tonic conductance in hippocampal neuronsCalcium/calmodulin-dependent protein kinase II mediates hippocampal glutamatergic plasticity during benzodiazepine withdrawal.Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies.Characterization of neurosteroid effects on hyperpolarizing current at α4β2δ GABAA receptors.Association of the GABRD gene and childhood-onset mood disordersPerimenstrual-like hormonal regulation of extrasynaptic δ-containing GABAA receptors mediating tonic inhibition and neurosteroid sensitivity.Down-regulation of synaptic GluN2B subunit-containing N-methyl-D-aspartate receptors: a physiological brake on CA1 neuron α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hyperexcitability during benzodiazepine withdrawalActivity-based anorexia during adolescence disrupts normal development of the CA1 pyramidal cells in the ventral hippocampus of female rats.GABAA receptor trafficking-mediated plasticity of inhibitory synapses.Chronic intermittent ethanol exposure produces persistent anxiety in adolescent and adult rats.Tyrosine phosphorylation of GABAA receptor γ2-subunit regulates tonic and phasic inhibition in the thalamus.The apparent voltage dependence of GABAA receptor activation and modulation is inversely related to channel open probability.Neurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse.Adolescent female rats exhibiting activity-based anorexia express elevated levels of GABA(A) receptor α4 and δ subunits at the plasma membrane of hippocampal CA1 spinesKnockout of the γ-aminobutyric acid receptor subunit α4 reduces functional δ-containing extrasynaptic receptors in hippocampal pyramidal cells at the onset of puberty.Ovarian hormone fluctuation, neurosteroids, and HPA axis dysregulation in perimenopausal depression: a novel heuristic model.Neurosteroids and GABA-A Receptor Function.Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy states
P2860
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P2860
Reversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at puberty
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@ast
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@en
type
label
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@ast
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@en
prefLabel
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@ast
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@en
P2093
P2860
P356
P1433
P1476
Reversal of neurosteroid effec ...... rs triggers anxiety at puberty
@en
P2093
Keith Williams
Maoli Yuan
Michael Dattilo
Qi Hua Gong
Yevgeniy Ruderman
P2860
P2888
P304
P356
10.1038/NN1868
P407
P577
2007-03-11T00:00:00Z