Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity
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Hexosamines, insulin resistance, and the complications of diabetes: current status.Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic propertiesThe role of glucosamine-induced ER stress in diabetic atherogenesisGLUT2 is a high affinity glucosamine transporterGlutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesisMammalian Tribbles homolog 3 impairs insulin action in skeletal muscle: role in glucose-induced insulin resistanceElevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytesAltered glycan-dependent signaling induces insulin resistance and hyperleptinemiaWeight Loss and the Prevention and Treatment of Type 2 Diabetes Using Lifestyle Therapy, Pharmacotherapy, and Bariatric Surgery: Mechanisms of Action.Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathwayA comprehensive review of oral glucosamine use and effects on glucose metabolism in normal and diabetic individualsPhysiological effects of oral glucosamine on joint health: current status and consensus on future research prioritiesAqueous fraction of Beta vulgaris ameliorates hyperglycemia in diabetic mice due to enhanced glucose stimulated insulin secretion, mediated by acetylcholine and GLP-1, and elevated glucose uptake via increased membrane bound GLUT4 transporters.Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats.Crystalline glucosamine sulfate in the treatment of osteoarthritis: evidence of long-term cardiovascular safety from clinical trials.Insulin resistance, metabolic stress, and atherosclerosis.Jicama (Pachyrhizus erosus) extract increases insulin sensitivity and regulates hepatic glucose in C57BL/Ksj-db/db mice.The reverse glucosamine sulfate pathway: application in knee osteoarthritis.Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies.SIRT1 attenuates high glucose-induced insulin resistance via reducing mitochondrial dysfunction in skeletal muscle cells.Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice.TRIB3 mediates glucose-induced insulin resistance via a mechanism that requires the hexosamine biosynthetic pathway.Role of the glucosamine pathway in fat-induced insulin resistance.Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus.Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistanceCentral nervous system nitric oxide synthase activity regulates insulin secretion and insulin action.The hexosamine biosynthesis pathway is essential for pancreatic beta cell development.Differential metabolic effects of glucosamine and N-acetylglucosamine in human articular chondrocytesThe efficacy and tolerability of glucosamine sulfate in the treatment of knee osteoarthritis: A randomized, double-blind, placebo-controlled trial.Glucosamine therapy for knee osteoarthritis: pharmacokinetic considerations.Na,K-ATPase regulation in skeletal muscle.Kinetic characterization of human glutamine-fructose-6-phosphate amidotransferase I: potent feedback inhibition by glucosamine 6-phosphate.[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hypergGlucosamine-induced insulin resistance in 3T3-L1 adipocytes.Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin Resistance.Increased flux through the hexosamine biosynthesis pathway inhibits glucose transport acutely by activation of protein kinase C.Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine.Possible role for gp160 in constitutive but not insulin-stimulated GLUT4 trafficking: dissociation of gp160 and GLUT4 localization.Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle.Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.
P2860
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P2860
Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Glucosamine induces insulin re ...... lications for glucose toxicity
@ast
Glucosamine induces insulin re ...... lications for glucose toxicity
@en
type
label
Glucosamine induces insulin re ...... lications for glucose toxicity
@ast
Glucosamine induces insulin re ...... lications for glucose toxicity
@en
prefLabel
Glucosamine induces insulin re ...... lications for glucose toxicity
@ast
Glucosamine induces insulin re ...... lications for glucose toxicity
@en
P2093
P2860
P356
P1476
Glucosamine induces insulin re ...... lications for glucose toxicity
@en
P2093
P2860
P304
P356
10.1172/JCI118349
P407
P577
1995-12-01T00:00:00Z