AMP-activated protein kinase regulates the assembly of epithelial tight junctions. - Wikidata - wikimedia - TriplyDB

AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

http://www.wikidata.org/entity/Q35768585

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The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK.The AMPK signalling pathway coordinates cell growth, autophagy and metabolism Emerging role of cell polarity proteins in breast cancer progression and metastasis AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK)A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression The LKB1-AMPK pathway: metabolism and growth control in tumour suppression AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.CaMKII regulates the strength of the epithelial barrier.AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts.Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro.LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1.The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis.Adiponectin increases secretion of rat submandibular gland via adiponectin receptors-mediated AMPK signaling.Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growth Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 Specific deletion of AMP-activated protein kinase (α1AMPK) in murine oocytes alters junctional protein expression and mitochondrial physiology Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic.Cellular mechanism of bile acid-accelerated hepatocyte polarity.Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization.LKB1 and AMPK maintain epithelial cell polarity under energetic stress.Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.Coordinated elevation of mitochondrial oxidative phosphorylation and autophagy help drive hepatocyte polarization.AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization.Hepatocyte polarity LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye.Epithelial junctions and polarity: complexes and kinases.Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane

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P2860

AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

http://www.wikidata.org/entity/Q35768585

description

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2006年论文

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name

AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

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Ji Li

http://www.w3.org/2001/XMLSchema#string

Lawrence H Young

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Li Zhang

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Michael J Caplan

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits

TSC2 mediates cellular energy response to control cell growth and survival

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

Roles of phosphatidylinositol 3'-kinase and mammalian target of rapamycin/p70 ribosomal protein S6 kinase in K-Ras-mediated transformation of intestinal epithelial cells

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

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