AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
about
The association of microtubules with tight junctions is promoted by cingulin phosphorylation by AMPK.The AMPK signalling pathway coordinates cell growth, autophagy and metabolismEmerging role of cell polarity proteins in breast cancer progression and metastasisAMP-activated protein kinase: an energy sensor that regulates all aspects of cell functionA kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamicsLKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domainLymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK)A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpressionThe LKB1-AMPK pathway: metabolism and growth control in tumour suppressionAMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.CaMKII regulates the strength of the epithelial barrier.AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts.Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro.LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1.The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis.Adiponectin increases secretion of rat submandibular gland via adiponectin receptors-mediated AMPK signaling.Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growthAugmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5Specific deletion of AMP-activated protein kinase (α1AMPK) in murine oocytes alters junctional protein expression and mitochondrial physiologyPreactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemiaAMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic.Cellular mechanism of bile acid-accelerated hepatocyte polarity.Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization.LKB1 and AMPK maintain epithelial cell polarity under energetic stress.Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesisLkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.Coordinated elevation of mitochondrial oxidative phosphorylation and autophagy help drive hepatocyte polarization.AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization.Hepatocyte polarityLKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activationBreaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye.Epithelial junctions and polarity: complexes and kinases.Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivoActivation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane
P2860
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P2860
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@ast
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@en
type
label
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@ast
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@en
prefLabel
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@ast
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@en
P2093
P2860
P356
P1476
AMP-activated protein kinase regulates the assembly of epithelial tight junctions.
@en
P2093
Lawrence H Young
Michael J Caplan
P2860
P304
17272-17277
P356
10.1073/PNAS.0608531103
P407
P577
2006-11-06T00:00:00Z