Mapping of the C5a receptor signal transduction network in human neutrophils.
about
Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathwayG protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexesFunction, structure and therapeutic potential of complement C5a receptorsCell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteinsComplement System Part II: Role in ImmunityChemotactic peptide-induced activation of MEK-2, the predominant isoform in human neutrophils. Inhibition by wortmanninNormal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout micePhospholipase D is required in the signaling pathway leading to p38 MAPK activation in neutrophil-like HL-60 cells, stimulated by N-formyl-methionyl-leucyl-phenylalanine.The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.Intracellular signaling by the chemokine receptor US28 during human cytomegalovirus infectionGenetic control of susceptibility to infection with Candida albicans in mice.Complement System Part I - Molecular Mechanisms of Activation and Regulation.Complementing the inflammasome.The role of the anaphylatoxins in health and disease.C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity.Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinasesMolecular interaction study of N1-p-fluorobenzyl-cymserine with TNF-α , p38 kinase and JNK kinase.Evidence that a lipolytic enzyme--hematopoietic-specific phospholipase C-β2--promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes.Functional coupling of adenosine A2a receptor to inhibition of the mitogen-activated protein kinase cascade in Chinese hamster ovary cells.Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.The Involvment of Hematopoietic-Specific PLC -β2 in Homing and Engraftment of Hematopoietic Stem/Progenitor Cells.Zebrafish as a model for the study of neutrophil biology.C5L2 Receptor Represses Brain-Derived Neurotrophic Factor Secretion in Lipoteichoic Acid-Stimulated Pulp Fibroblasts.C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and β-arrestin recruitment.Signals and receptors involved in recruitment of inflammatory cells.Probing the "message:address" sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segments.Induction of cytosolic phospholipase A2 activity by phosphatidic acid and diglycerides in permeabilized human neutrophils: interrelationship between phospholipases D and A2.Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion productionCytosolic phospholipase A2 and its mode of activation in human neutrophils by opsonized zymosan. Correlation between 42/44 kDa mitogen-activated protein kinase, cytosolic phospholipase A2 and NADPH oxidaseActivation of mitogen-activated protein kinases by formyl peptide receptors is regulated by the cytoplasmic tail.Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction.Is raf-1 the 74 kDa signalling molecule in neutrophils?C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.Tumor necrosis factor-alpha activation of the c-Jun N-terminal kinase pathway in human neutrophils. Integrin involvement in a pathway leading from cytoplasmic tyrosine kinases apoptosis.Phagocyte chemoattractant receptors.Inflammation and anti-inflammation: gating of cell/cell adhesion at the level of mitogen-activated protein kinases.The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway.
P2860
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P2860
Mapping of the C5a receptor signal transduction network in human neutrophils.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Mapping of the C5a receptor signal transduction network in human neutrophils.
@ast
Mapping of the C5a receptor signal transduction network in human neutrophils.
@en
type
label
Mapping of the C5a receptor signal transduction network in human neutrophils.
@ast
Mapping of the C5a receptor signal transduction network in human neutrophils.
@en
prefLabel
Mapping of the C5a receptor signal transduction network in human neutrophils.
@ast
Mapping of the C5a receptor signal transduction network in human neutrophils.
@en
P2093
P2860
P356
P1476
Mapping of the C5a receptor signal transduction network in human neutrophils.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.19.9190
P407
P577
1994-09-01T00:00:00Z