Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma - Wikidata - wikimedia - TriplyDB

Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

http://www.wikidata.org/entity/Q35780214

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VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex Remodelling the extracellular matrix in development and disease The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair Heparan sulfate signaling in cancer A combinatorial radiographic phenotype may stratify patient survival and be associated with invasion and proliferation characteristics in glioblastoma Substrate specificity of 6-O-endosulfatase (Sulf-2) and its implications in synthesizing anticoagulant heparan sulfate.Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling Oligosaccharide substrate preferences of human extracellular sulfatase Sulf2 using liquid chromatography-mass spectrometry based glycomics approaches.MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival.Inhibition of Phosphatase Activity Follows Decline in Sulfatase Activity and Leads to Transcriptional Effects through Sustained Phosphorylation of Transcription Factor MITF.Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity.Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing.Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts.Glioblastoma--a moving target.SULF2 Expression Is a Potential Diagnostic and Prognostic Marker in Lung Cancer.Novel therapeutic targets in the brain tumor microenvironment SULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study.Proteoglycans and their roles in brain cancer.Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity.What underlies the diversity of brain tumors?The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.Heparan sulfate in the regulation of neural differentiation and glioma development.Sugar glues for broken neurons The "in and out" of glucosamine 6-O-sulfation: the 6th sense of heparan sulfate.Glycosylation alterations in lung and brain cancer.Sulfatase-2: a prognostic biomarker and candidate therapeutic target in patients with pancreatic ductal adenocarcinoma Antiproliferative activity of Juglone derivatives on rat glioma.Differentially Expressed Long Non-Coding RNAs Were Predicted to Be Involved in the Control of Signaling Pathways in Pediatric Astrocytoma.Integrating the glioblastoma microenvironment into engineered experimental models.Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA Mass spectral profiling of glycosaminoglycans from histological tissue surfaces.Heparan Sulfate Glycosaminoglycans in Glioblastoma Promote Tumor Invasion.Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference.Measuring sulfatase expression and invasion in glioblastoma.Heparan Sulfate Biosynthetic System Is Inhibited in Human Glioma Due to EXT1/2 and HS6ST1/2 Down-Regulation.Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype.Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.Specific inhibition of secreted NRG1 types I-II by heparin enhances Schwann Cell myelination Heparan Sulfate and Heparan Sulfate Proteoglycans in Cancer Initiation and Progression

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Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma

http://www.wikidata.org/entity/Q35780214

description

2012 nî lūn-bûn

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2012年论文

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2012年论文

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Journal of Clinical Investigation

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Heparan sulfate sulfatase SULF ...... man and mouse malignant glioma

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Aaron E Robinson

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Anna Ward

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David H Lum

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David H Rowitch

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Emmanuelle Huillard

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Joanna J Phillips

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Mei-Yin Polley

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Steven D Rosen

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Zena Werb

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P2860

Vascular endothelial growth factor can signal through platelet-derived growth factor receptors

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling

Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

A role of PDGFRalpha in basal cell carcinoma proliferation

An integrated genomic analysis of human glioblastoma multiforme

Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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3287216

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