Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5. - Wikidata - wikimedia - TriplyDB

Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5.

Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5.

http://www.wikidata.org/entity/Q35787055

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Channelopathies Intracellular Molecular Differences in Aldosterone- Compared to Cortisol-Secreting Adrenal Cortical Adenomas Role of ACTH and Other Hormones in the Regulation of Aldosterone Production in Primary Aldosteronism Role of the Renin-Angiotensin-Aldosterone System beyond Blood Pressure Regulation: Molecular and Cellular Mechanisms Involved in End-Organ Damage during Arterial Hypertension Genetic alterations in primary aldosteronism Gene mutations that promote adrenal aldosterone production, sodium retention, and hypertension Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas Primary Aldosteronism: Changing Definitions and New Concepts of Physiology and Pathophysiology Both Inside and Outside the Kidney.Overview of the genetic determinants of primary aldosteronism.Minireview: potassium channels and aldosterone dysregulation: is primary aldosteronism a potassium channelopathy?The Future of "Omics" in Hypertension.Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium Ion channel associated diseases: overview of molecular mechanisms Comprehensive re-sequencing of adrenal aldosterone producing lesions reveal three somatic mutations near the KCNJ5 potassium channel selectivity filter.Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism Uncoupling of secretion from growth in some hormone secretory tissues.Genetic variations in the KCNJ5 gene in primary aldosteronism patients from Xinjiang, China A case of severe hyperaldosteronism caused by a de novo mutation affecting a critical salt bridge Kir3.4 residue.Understanding primary aldosteronism: impact of next generation sequencing and expression profiling.Management of Resistant Hypertension: Do Not Give Up on Medication.Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas.Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism.Two-pore domain potassium channels in the adrenal cortex.Primary Aldosteronism and ARMC5 Variants.Molecular and Cellular Mechanisms of Aldosterone Producing Adenoma Development Prevalence and clinical correlates of somatic mutation in aldosterone producing adenoma-Taiwanese population Altered and dynamic ion selectivity of K+ channels in cell development and excitability A novel point mutation in the KCNJ5 gene causing primary hyperaldosteronism and early-onset autosomal dominant hypertension.Different Somatic Mutations in Multinodular Adrenals With Aldosterone-Producing Adenoma.Prevalence and characterization of somatic mutations in Chinese aldosterone-producing adenoma patients.The potassium channel, Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line The Challenges of Arterial Hypertension.cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse.Immunohistochemistry of the adrenal in primary aldosteronism Mutated KCNJ5 activates the acute and chronic regulatory steps in aldosterone production a Novel Y152C KCNJ5 mutation responsible for familial hyperaldosteronism type III.CACNA1H Mutations Are Associated With Different Forms of Primary Aldosteronism.Integrated analysis of genome-wide methylation and gene expression shows epigenetic regulation of CYP11B2 in aldosteronomas.Primary aldosteronism: a channelopathy?

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P2860

Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5.

http://www.wikidata.org/entity/Q35787055

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Proceedings of the National Academy of Sciences of the United States of America

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Hypertension with or without a ...... n the potassium channel KCNJ5.

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Anita Farhi

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Carol Nelson-Williams

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Frances L Harley

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Lisa K Hammer

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Michael J Dillon

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Peng Yue

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Richard P Lifton

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Robert Couch

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Roger Grekin

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Ute I Scholl

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P2860

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report

An ACTH- and ATP-regulated background K+ channel in adrenocortical cells is TREK-1

The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins

Global burden of hypertension: analysis of worldwide data

Molecular mechanisms of human hypertension.

Mutations in the K+ channel signature sequence.

K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension

Adrenocortical stem and progenitor cells: unifying model of two proposed origins.

Genetic dissection of human blood pressure variation: common pathways from rare phenotypes.

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