Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation - Wikidata - wikimedia - TriplyDB

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

http://www.wikidata.org/entity/Q35788867

about

Cellular and molecular mechanisms of fibrosis Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity Role of endoglin in fibrosis and scleroderma The Contribution of Peroxisome Proliferator-Activated Receptor Gamma to Cutaneous Wound Healing Ionizing radiation: the good, the bad, and the ugly Key Fibrogenic Signaling Endothelial perturbations and therapeutic strategies in normal tissue radiation damage The TGF-β/Smad repressor TG-interacting factor 1 (TGIF1) plays a role in radiation-induced intestinal injury independently of a Smad signaling pathway Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3 Pulmonary fibrosis: pathogenesis, etiology and regulation RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization Radiotherapy-Induced Skin Reactions Induce Fibrosis Mediated by TGF-β1 Cytokine Halofuginone enhances the radiation sensitivity of human tumor cell lines Medical applications of transforming growth factor-beta Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis.Smad3 knock-out mice as a useful model to study intestinal fibrogenesis Molecular mechanisms and treatment of radiation-induced lung fibrosis Radiation therapy causes loss of dermal lymphatic vessels and interferes with lymphatic function by TGF-beta1-mediated tissue fibrosis.Transforming growth factor-beta and fibrosis Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials Blockade of transforming growth factor-beta1 accelerates lymphatic regeneration during wound repair.Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease Adaptive and maladptive effects of SMAD3 signaling in the adult heart after hemodynamic pressure overloading Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis.The role of p53 in determining sensitivity to radiotherapy.Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury.Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29 Cytochrome P450 epoxygenase CYP2J2 attenuates nephropathy in streptozotocin-induced diabetic mice Targeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy.Histone acetyltransferase inhibitor C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192.Smad3 as a mediator of the fibrotic response.Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy.Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin.

P2860

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P2860

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

http://www.wikidata.org/entity/Q35788867

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

@zh-hk

2002年論文

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2002年論文

@zh-tw

2002年论文

@wuu

2002年论文

@zh

2002年论文

@zh-cn

name

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@ast

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@en

type

label

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@ast

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@en

prefLabel

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@ast

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@en

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S0002-9440(10)64926-7

P1433

The American Journal of Pathology

P1476

Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation

@en

P2093

Alidad Arabshahi

http://www.w3.org/2001/XMLSchema#string

Anastasia Sowers

http://www.w3.org/2001/XMLSchema#string

Angelo Russo

http://www.w3.org/2001/XMLSchema#string

Catherine D Sullivan

http://www.w3.org/2001/XMLSchema#string

Christopher Major

http://www.w3.org/2001/XMLSchema#string

Chuxia Deng

http://www.w3.org/2001/XMLSchema#string

James B Mitchell

http://www.w3.org/2001/XMLSchema#string

Kathleen C Flanders

http://www.w3.org/2001/XMLSchema#string

Makiko Fujii

http://www.w3.org/2001/XMLSchema#string

Mario A Anzano

http://www.w3.org/2001/XMLSchema#string

P2860

Role of transforming growth factor-beta signaling in cancer

Regulation of Smad signaling by protein kinase C

Transforming growth factor beta in tissue fibrosis

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

Human Smad3 and Smad4 are sequence-specific transcription activators

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

How cells read TGF-beta signals

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1057-1068

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10.1016/S0002-9440(10)64926-7

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11472562

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11891202

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1867194

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