AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity
about
Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense functionEstablishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonistsTreatment of allergic asthma: modulation of Th2 cells and their responsesChemokine receptors and their therapeutic opportunities in diseased lung: far beyond leukocyte traffickingCXC chemokine receptor-4 signaling limits hepatocyte proliferation after hepatic ischemia-reperfusion in mice.i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4.Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrowSmall neutralizing molecules to inhibit actions of the chemokine CXCL12.An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.Effect of CXCL12/CXCR4 signaling on neuropathic pain after chronic compression of dorsal root ganglionTargeted antagonism of CXCR4 mobilizes progenitor cells under investigation for cardiovascular disease.Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis.The chemokine CXCL12 is essential for the clearance of the filaria Litomosoides sigmodontis in resistant miceAnalysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD).AMD3465, a novel CXCR4 receptor antagonist, abrogates schistosomal antigen-elicited (type-2) pulmonary granuloma formation.Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system.IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cellsAn important role of the SDF-1/CXCR4 axis in chronic skin inflammationExamination of structure-activity relationship of viologen-based dendrimers as CXCR4 antagonists and gene carriers.Enhancement of T cell recruitment and infiltration into tumours.Chemokines in allergic airway disease.The role of chemokines and chemokine receptors in eosinophil activation during inflammatory allergic reactions.Cell, isoform, and environment factors shape gradients and modulate chemotaxisCXCR4 blockade attenuates hyperoxia-induced lung injury in neonatal ratsInhibition of CXCL12-mediated chemotaxis of Jurkat cells by direct immunotoxicants.Interleukin-16 and peptide derivatives as immunomodulatory therapy in allergic lung disease.Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.CXCR4 inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 and ERK1/2Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases.New chemokine targets for asthma therapy.Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).Inhibition of Porphyromonas gingivalis-induced periodontal bone loss by CXCR4 antagonist treatment.Chemokine receptors : therapeutic potential in asthma.Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells.An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in miceThe CXCR4 chemokine receptor in acute and chronic leukaemia: a marrow homing receptor and potential therapeutic target.CXCR4 inhibitor attenuates ovalbumin-induced airway inflammation and hyperresponsiveness by inhibiting Th17 and Tc17 cell immune response.Chemokines and their receptors in respiratory disease: a therapeutic target for respiratory syncytial virus infection.The cytokine network in asthma and chronic obstructive pulmonary diseaseAttenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model.
P2860
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P2860
AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@ast
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@en
type
label
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@ast
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@en
prefLabel
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@ast
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@en
P2093
P2860
P1476
AMD3100, a CxCR4 antagonist, a ...... ion and airway hyperreactivity
@en
P2093
Aaron Berlin
Gary J Bridger
Nicholas W Lukacs
Renato T Skerlj
P2860
P304
P356
10.1016/S0002-9440(10)62562-X
P407
P577
2002-04-01T00:00:00Z