Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
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LRP-1: a checkpoint for the extracellular matrix proteolysisTIMP1 promotes multi-walled carbon nanotube-induced lung fibrosis by stimulating fibroblast activation and proliferationAnti-cancer activity of a novel small molecule compound that simultaneously activates p53 and inhibits NF-κB signalingExpression and Subcellular Distribution of GFP-Tagged Human Tetraspanin Proteins in Saccharomyces cerevisiaeTargeting pathways downstream of KRAS in lung adenocarcinoma.Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancerIKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity.Epidermal p65/NF-κB signalling is essential for skin carcinogenesisNF-κB, an active player in human cancers.TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling.CDA-2, a urinary preparation, inhibits lung cancer development through the suppression of NF-kappaB activation in myeloid cell.A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycinA versatile modular vector system for rapid combinatorial mammalian geneticsNKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation.The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damageTIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling.Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma.A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβTargeting NF-κB in glioblastoma: A therapeutic approachActive IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma.Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.Dioxonaphthoimidazoliums AB1 and YM155 disrupt phosphorylation of p50 in the NF-κB pathwayNeutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer.TIMP-1 and CD82, a promising combined evaluation marker for PDAC.Mouse models for lung cancerRoles of matrix metalloproteinases and their natural inhibitors in prostate cancer progression.Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets.Elevated circulating tissue inhibitor of metalloproteinase 1 (TIMP-1) levels are associated with neuroendocrine differentiation in castration resistant prostate cancer.Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes.Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis.Novel treatment for mantle cell lymphoma including therapy-resistant tumor by NF-κB and mTOR dual-targeting approach.GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κB.Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment.RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesisOpening a new GATAway for treating KRAS-driven lung tumors.RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation.Context-Dependent Role of IKKβ in Cancer.IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.Non-canonical IKKs, IKKϵ and TBK1, as novel therapeutic targets in the treatment of non-small cell lung cancer.Tissue inhibitor of metalloproteinase-1 promotes cell proliferation through YAP/TAZ activation in cancer.
P2860
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P2860
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@ast
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@en
type
label
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@ast
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@en
prefLabel
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@ast
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@en
P2093
P2860
P356
P1433
P1476
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model.
@en
P2093
Eric Oldfield
Inder M Verma
Mathias Leblanc
Narayana Yeddula
Reuben J Shaw
Yifeng Xia
Yonghui Zhang
P2860
P2888
P304
P356
10.1038/NCB2428
P577
2012-02-12T00:00:00Z