Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease.
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Neurodegeneration with brain iron accumulation: update on pathogenic mechanismsMitochondrial CardiomyopathiesIron and sulfur in proteins. How does the cell build Fe-S clusters, cofactors essential for life?Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster deliveryUnderstanding the genetic and molecular pathogenesis of Friedreich's ataxia through animal and cellular modelsThe role of mitochondria in cellular iron-sulfur protein biogenesis: mechanisms, connected processes, and diseasesFunctional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxinThe mitochondrial carrier Rim2 co-imports pyrimidine nucleotides and iron.Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins.The iron metallome in eukaryotic organismsVariant non ketotic hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemInteractions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseTurning Escherichia coli into a Frataxin-Dependent OrganismCerebellar pathology in Friedreich's ataxia: atrophied dentate nuclei with normal iron content.Formation, spectroscopic characterization, and solution stability of an [Fe4S4]2+ cluster derived from β-cyclodextrin dithiolate.Frataxin-bypassing Isu1: characterization of the bypass activity in cells and mitochondriaTargeting Iron Homeostasis in Acute Kidney Injury.Davis-Beirut reaction: route to thiazolo-, thiazino-, and thiazepino-2H-indazoles.Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control.Interaction between Nbp35 and Cfd1 proteins of cytosolic Fe-S cluster assembly reveals a stable complex formation in Entamoeba histolyticaThe Succinated Proteome of FH-Mutant TumoursHIBCH mutations can cause Leigh-like disease with combined deficiency of multiple mitochondrial respiratory chain enzymes and pyruvate dehydrogenase.The specialized Hsp70 (HscA) interdomain linker binds to its nucleotide-binding domain and stimulates ATP hydrolysis in both cis and trans configurations.Genome-wide identification of whole ATP-binding cassette (ABC) transporters in the intertidal copepod Tigriopus japonicus.Fe-S cluster biogenesis in isolated mammalian mitochondria: coordinated use of persulfide sulfur and iron and requirements for GTP, NADH, and ATP.The functions of cardiolipin in cellular metabolism-potential modifiers of the Barth syndrome phenotypeGene expression profiling of mitochondrial oxidative phosphorylation (OXPHOS) complex I in Friedreich ataxia (FRDA) patients.Tangled web of interactions among proteins involved in iron-sulfur cluster assembly as unraveled by NMR, SAXS, chemical crosslinking, and functional studies.Duodenal cytochrome b (DCYTB) in iron metabolism: an update on function and regulation.Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect.Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.MET18 Connects the Cytosolic Iron-Sulfur Cluster Assembly Pathway to Active DNA Demethylation in Arabidopsis.The N-terminal Domain of Escherichia coli Assimilatory NADPH-Sulfite Reductase Hemoprotein Is an Oligomerization Domain That Mediates Holoenzyme Assembly.Tissue specificity of a human mitochondrial disease: differentiation-enhanced mis-splicing of the Fe-S scaffold gene ISCU renders patient cells more sensitive to oxidative stress in ISCU myopathy.The E. coli SufS-SufE sulfur transfer system is more resistant to oxidative stress than IscS-IscU.Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors.Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron-sulfur cluster enzyme activities and impaired iron homeostasis.Physical and functional interactions of a monothiol glutaredoxin and an iron sulfur cluster carrier protein with the sulfur-donating radical S-adenosyl-L-methionine enzyme MiaB[2Fe-2S]-ferredoxin binds directly to cysteine desulfurase and supplies an electron for iron-sulfur cluster assembly but is displaced by the scaffold protein or bacterial frataxin.
P2860
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P2860
Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@ast
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@en
type
label
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@ast
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@en
prefLabel
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@ast
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@en
P2860
P356
P1476
Biogenesis of iron-sulfur clus ...... nd relevance to human disease.
@en
P2093
Tracey A Rouault
P2860
P304
P356
10.1242/DMM.009019
P577
2012-03-01T00:00:00Z