Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
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Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-IModeling human influenza infection in the laboratoryInduction of innate immunity and its perturbation by influenza virusesThe role of host genetics in susceptibility to influenza: a systematic reviewS. mansoni bolsters anti-viral immunity in the murine respiratory tractEvidence-Based Biosafety: a Review of the Principles and Effectiveness of Microbiological Containment MeasuresInterferon-inducible antiviral effectorsTmprss2 is essential for influenza H1N1 virus pathogenesis in mice.Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in miceThe Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.Molecular determinants of influenza virus pathogenesis in mice.Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumoniaInfluenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPaseThe nucleoprotein of newly emerged H7N9 influenza A virus harbors a unique motif conferring resistance to antiviral human MxA.Heterosubtypic immunity to influenza A virus: where do we stand?Intranasal administration of alpha interferon reduces seasonal influenza A virus morbidity in ferretsHuman Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses.Alternative live-attenuated influenza vaccines based on modifications in the polymerase genes protect against epidemic and pandemic flu.Rapid control of pandemic H1N1 influenza by targeting NKT-cells.Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survivalPseudotyped influenza A virus as a vaccine for the induction of heterotypic immunityH5N1 pathogenesis studies in mammalian models.Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza A virus that expresses an altered nucleoprotein sequence.In vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies.Host genetic background strongly influences the response to influenza a virus infections.Molecular determinants of adaptation of highly pathogenic avian influenza H7N7 viruses to efficient replication in the human hostInnate immune evasion strategies of influenza virusesOromucosal Administration of Interferon to HumansThe cytoplasmic location of chicken mx is not the determining factor for its lack of antiviral activitySTAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.Species-specific contribution of the four C-terminal amino acids of influenza A virus NS1 protein to virulence.Temporal and spatial resolution of type I and III interferon responses in vivo.Tick-borne encephalitis virus delays interferon induction and hides its double-stranded RNA in intracellular membrane vesicles.Identification and characterization of a novel non-structural protein of bluetongue virus.PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virusGlycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon response.Biodegradable nanogels for oral delivery of interferon for norovirus infectionStress-induced reversion to virulence of infectious pancreatic necrosis virus in naïve fry of Atlantic salmon (Salmo salar L.).Animal Models for Influenza Virus Pathogenesis and Transmission.Animal models for influenza viruses: implications for universal vaccine development
P2860
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P2860
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Replication fitness determines ...... functional Mx1 resistance gene
@ast
Replication fitness determines ...... functional Mx1 resistance gene
@en
type
label
Replication fitness determines ...... functional Mx1 resistance gene
@ast
Replication fitness determines ...... functional Mx1 resistance gene
@en
prefLabel
Replication fitness determines ...... functional Mx1 resistance gene
@ast
Replication fitness determines ...... functional Mx1 resistance gene
@en
P2093
P2860
P50
P356
P1476
Replication fitness determines ...... functional Mx1 resistance gene
@en
P2093
Daniel Grimm
Georg Kochs
Iris Koerner
Martin Hufbauer
Otto Haller
Peter Staeheli
P2860
P304
P356
10.1073/PNAS.0701849104
P407
P577
2007-04-10T00:00:00Z