SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer
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Signaling Pathways in Thyroid Cancer and Their Therapeutic ImplicationsRe-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpointsCombined BRAF(V600E)- and SRC-inhibition induces apoptosis, evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid cancer.Cowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation.Src inhibitors in suppression of papillary thyroid carcinoma growth.Thyroid hormone receptors and cancer.Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actionsThe role of Src kinase in macrophage-mediated inflammatory responses.Reactivation of the silenced thyroid hormone receptor β gene expression delays thyroid tumor progressionDiet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse modelComplex temporal changes in TGFβ oncogenic signaling drive thyroid carcinogenesis in a mouse modelPreliminary results of a non-invasive method to measure tumor size and distribution in vivo.Inhibition of tumorigenesis by the thyroid hormone receptor β in xenograft models.An in vivo mouse model of metastatic human thyroid cancerMeaningful prevention of breast cancer metastasis: candidate therapeutics, preclinical validation, and clinical trial concerns.Modeling anaplastic thyroid carcinoma in the mouse.Natural Killer Cell (NK-92MI)-Based Therapy for Pulmonary Metastasis of Anaplastic Thyroid Cancer in a Nude Mouse Model.Sustained activation of the AKT/mTOR and MAP kinase pathways mediate resistance to the Src inhibitor, dasatinib, in thyroid cancer.The association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer.Endocrine Disorders
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P2860
SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer
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2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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name
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@ast
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@en
type
label
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@ast
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@en
prefLabel
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@ast
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@en
P2093
P2860
P1476
SKI-606, an Src inhibitor, red ...... mouse model of thyroid cancer
@en
P2093
Celine J Guigon
Changxue Lu
Jeong Won Park
Laura Fozzatti
Mark C Willingham
Sheue-yann Cheng
Won Gu Kim
P2860
P304
P356
10.1158/1078-0432.CCR-11-2892
P407
P577
2012-01-23T00:00:00Z