Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance.

Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance.

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http://www.wikidata.org/entity/Q35804739
Functional Studies of ssDNA Binding Ability of MarR Family Protein TcaR from Staphylococcus epidermidisA novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activityAn intravenous (i.v.) route-compatible formulation of FL118, a survivin, Mcl-1, XIAP, and cIAP2 selective inhibitor, improves FL118 antitumor efficacy and therapeutic index (TI)Generation of a novel transgenic mouse model for bioluminescent monitoring of survivin gene activity in vivo at various pathophysiological processes: survivin expression overlaps with stem cell markersA cell-permeable dominant-negative survivin protein induces apoptosis and sensitizes prostate cancer cells to TNF-α therapy.Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo.Suppression of survivin promoter activity by YM155 involves disruption of Sp1-DNA interaction in the survivin core promoter.Enhancing effectiveness of the MDR-sensitive compound T138067 using advanced treatment with negative modulators of the drug-resistant protein survivin.Transcriptional inhibition of p21WAF1/CIP1 gene (CDKN1) expression by survivin is at least partially p53-dependent: evidence for survivin acting as a transcription factor or co-factor.Chemotherapeutic efficacies of a clofazimine and diminazene aceturate combination against piroplasm parasites and their AT-rich DNA-binding activity on Babesia bovis.Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?
P2860

Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance.

Item
http://www.wikidata.org/entity/Q35804739
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年論文
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2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
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2007年論文
@zh-tw
2007年论文
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2007年论文
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2007年论文
@zh-cn
name
Molecular mechanism of upregul ...... nvolvement in drug resistance.
@ast
Molecular mechanism of upregul ...... nvolvement in drug resistance.
@en
type
label
Molecular mechanism of upregul ...... nvolvement in drug resistance.
@ast
Molecular mechanism of upregul ...... nvolvement in drug resistance.
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prefLabel
Molecular mechanism of upregul ...... nvolvement in drug resistance.
@ast
Molecular mechanism of upregul ...... nvolvement in drug resistance.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
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P1433
P1476
Molecular mechanism of upregul ...... involvement in drug resistance
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932