A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment.
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Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maizeHistopathological Evaluation of Contrast-Induced Acute Kidney Injury Rodent ModelsDevelopment of a novel transgenic rat overexpressing the P2Y(2) nucleotide receptor using a lentiviral vectorMitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneysDeriving a data-based interspecies assessment factor using the NOAEL and the benchmark dose approach.Recommendations for the interpretation of renal tubule proliferative lesions occurring in rat kidneys with advanced chronic progressive nephropathy (CPN).Histological investigation of diagnostically challenging tubule profiles in advanced chronic progressive nephropathy (CPN) in the fischer 344 RaT.Physiologically based pharmacokinetic model for ethyl tertiary-butyl ether and tertiary-butyl alcohol in rats: Contribution of binding to α2u-globulin in male rats and high-exposure nonlinear kinetics to toxicity and cancer outcomes.Carcinogenicity risk assessment supports the chronic safety of dapagliflozin, an inhibitor of sodium-glucose co-transporter 2, in the treatment of type 2 diabetes mellitus.Spontaneous occurrence of a distinctive renal tubule tumor phenotype in rat carcinogenicity studies conducted by the national toxicology programAssociation of advanced chronic progressive nephropathy (CPN) with renal tubule tumors and precursor hyperplasia in control F344 rats from two-year carcinogenicity studies.Left ventricular hypertrophy is prevalent in Sprague-Dawley rats.Nonclinical safety profile of telbivudine, a novel potent antiviral agent for treatment of hepatitis BChronic carcinogenicity study of gasoline vapor condensate (GVC) and GVC containing methyl tertiary-butyl ether in F344 ratsModerate exercise during pregnancy in Wistar rats alters bone and body composition of the adult offspring in a sex-dependent mannerAcute Oral or Dermal and Repeated Dose 90-Day Oral Toxicity of Tetrasodium Pyrophosphate in Spraque Dawley (SD) Rats.Four-Week Repeated Intravenous Dose Toxicity and Toxicokinetic Study of TS-DP2, a Novel Human Granulocyte Colony Stimulating Factor in Rats.Consideration of rat chronic progressive nephropathy in regulatory evaluations for carcinogenicity.Ethyl tertiary-butyl ether: a toxicological review.Stress-reactive rats (high-avoidance female rats) have a shorter lifespan than stress-nonreactive rats (low-avoidance female rats).Hydroquinone: an evaluation of the human risks from its carcinogenic and mutagenic properties.Loss of leucine-rich repeat kinase 2 (LRRK2) in rats leads to progressive abnormal phenotypes in peripheral organsA comparison of rat chronic progressive nephropathy with human renal disease-implications for human risk assessment.Tertiary-Butanol: a toxicological review.Are rats the appropriate experimental model to understand age-related renal drug metabolism and toxicity?Best practices for clinical pathology testing in carcinogenicity studies.Glomerulonephropathy in aged captive Key Largo woodrats (Neotoma floridana smalli).Human health screening level risk assessments of tertiary-butyl acetate (TBAC): calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations.Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4).Successful integration of nonclinical and clinical findings in interpreting the clinical relevance of rodent neoplasia with a new chemical entity.Aging in the Canine Kidney.Characterizing "Adversity" of Pathology Findings in Nonclinical Toxicity Studies: Results from the 4th ESTP International Expert Workshop.Regulatory Forum commentary: alternative mouse models for future cancer risk assessment.Findings in Historical Control Harlan RCCHan™: WIST Rats from 104-week Oral Gavage Studies.Regulatory Forum Opinion Piece*: Dispelling Confusing Pathology Terminology: Recognition and Interpretation of Selected Rodent Renal Tubule Lesions.Chronic progressive nephropathy: functional, morphological, and morphometrical studies.A 26-week repeated-dose toxicity study of allisartan isoproxil in Sprague-Dawley rats.Findings in Historical Control Harlan RCCHanTM: WIST Rats from 4-, 13-, 26-Week Studies.Re-evaluation of kidney histopathology from 13-week toxicity and two-year carcinogenicity studies of melamine in the F344 rat: morphologic evidence of retrograde nephropathy.Nonclinical safety evaluation of sunitinib: a potent inhibitor of VEGF, PDGF, KIT, FLT3, and RET receptors.
P2860
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P2860
A contemporary overview of chronic progressive nephropathy in the laboratory rat, and its significance for human risk assessment.
description
2004 nî lūn-bûn
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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2004年论文
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2004年论文
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name
A contemporary overview of chr ...... nce for human risk assessment.
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A contemporary overview of chr ...... nce for human risk assessment.
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type
label
A contemporary overview of chr ...... nce for human risk assessment.
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A contemporary overview of chr ...... nce for human risk assessment.
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prefLabel
A contemporary overview of chr ...... nce for human risk assessment.
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A contemporary overview of chr ...... nce for human risk assessment.
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P2860
P1476
A contemporary overview of chr ...... nce for human risk assessment.
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P2093
Gordon C Hard
Kanwar Nasir Khan
P2860
P304
P356
10.1080/01926230490422574
P407
P577
2004-03-01T00:00:00Z