Angiotensin II induces epithelial-to-mesenchymal transition in renal epithelial cells through reactive oxygen species/Src/caveolin-mediated activation of an epidermal growth factor receptor-extracellular signal-regulated kinase signaling pathway.
about
Key fibrogenic mediators: old players. Renin–angiotensin systemCell-surface receptors transactivation mediated by g protein-coupled receptorsUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesRole and therapeutic potential of G-protein coupled receptors in breast cancer progression and metastasesEpidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular SystemCaveolin-1 is required for kinase suppressor of Ras 1 (KSR1)-mediated extracellular signal-regulated kinase 1/2 activation, H-RasV12-induced senescence, and transformationImplications of human genome structural heterogeneity: functionally related genes tend to reside in organizationally similar genomic regions.Suppression of XBP1S mediates high glucose-induced oxidative stress and extracellular matrix synthesis in renal mesangial cell and kidney of diabetic rats.Role of the urokinase-fibrinolytic system in epithelial-mesenchymal transition during lung injury.Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways.Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease.EGF receptor deletion in podocytes attenuates diabetic nephropathy.Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis.Gene Silencing and Haploinsufficiency of Csk Increase Blood PressureEffect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells.International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].Rift Valley fever virus strain MP-12 enters mammalian host cells via caveola-mediated endocytosis.ADAM17 substrate release in proximal tubule drives kidney fibrosisDiabetes and Kidney Disease: Role of Oxidative Stress.Inhibition of nuclear Nox4 activity by plumbagin: effect on proliferative capacity in human amniotic stem cells.Src tyrosine kinase mediates platelet-derived growth factor BB-induced and redox-dependent migration in metanephric mesenchymal cells.Nox4 and diabetic nephropathy: with a friend like this, who needs enemies?To RAS or not to RAS? The evidence for and cautions with renin-angiotensin system inhibition in patients with diabetic kidney disease.Cellular functions regulated by phosphorylation of EGFR on Tyr845.JAK inhibition and progressive kidney disease.Nox and renal disease.Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts.Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion.Caveolin-1 in the Pathogenesis of Diabetic Nephropathy: Potential Therapeutic Target?Role of TGF-alpha in the progression of diabetic kidney disease.Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis.Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion.Is There a Potential Therapeutic Role for Caveolin-1 in Fibrosis?Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1.Regulation of anoikis resistance by NADPH oxidase 4 and epidermal growth factor receptor.Binding of prorenin to (pro)renin receptor induces the proliferation of human umbilical artery smooth muscle cells via ROS generation and ERK1/2 activation.A Pathogenic Mechanism Potentially Operative in Multiple Progressive Diseases and Its Therapeutic Implications.Erlotinib attenuates the progression of chronic kidney disease in rats with remnant kidney.Dissecting Cell-Fate Determination Through Integrated Mathematical Modeling of the ERK/MAPK Signaling Pathway.The mitochondrial-targeted peptide, SS-31, improves glomerular architecture in mice of advanced age.
P2860
Q26796631-63DC8FE6-FECB-46FC-923D-076DC688C4C5Q26827583-02A29E13-507A-44FF-960A-B1CD4699D1B0Q27008332-80C90AB0-BA61-4BED-85D5-A73F46290CB5Q28084420-A324996A-FF7D-4821-BE5E-5552E99BC357Q33814199-8702D78C-D3B5-410E-A085-9F4CFF0A8DA5Q34056599-20398D16-9BB3-4375-9C02-B8E65450935FQ34525787-B80269A1-BBEA-434A-8821-A8BB04DB2660Q34606527-39B50DE3-5335-4B18-981E-733DAE3661E7Q34780769-79A06697-C0B6-4721-8F47-1C38D82033D9Q35009145-D3D0D13B-3696-4F31-B07B-21F8855FD0F3Q35450699-BB6565EB-DC96-4E0B-AAEA-8B3B3C448E1FQ35550573-E702CB01-C5E3-4A15-9096-331E62F08246Q35790612-DBDC1F44-5729-425A-8CC4-392349B3B9D4Q35890054-2352909A-4565-4DB1-BDB3-05B64946AF4BQ36061883-B95D615A-05BD-4F11-AFB6-F25E06770B69Q36241932-4BC37FEE-C841-4CF2-BFD1-8A155A5F9470Q36397378-585E6FD1-D086-4355-AFF8-717D28C19D3EQ37262336-B1A7B7C3-DE33-48A2-A0C7-2F9F9AB32CFCQ37349206-54610715-8C12-44F0-9C4D-88CD59E205A0Q37486972-76E23F90-20A2-4494-9855-70EAEE4A2D91Q37579198-EDA659DC-9328-4DC1-BB32-3F5CACA131C6Q38092960-E2604377-3426-47D4-B2BB-07148DE22BD1Q38098108-028A588E-B55B-459C-9425-220685A08C4FQ38109021-2D06E39D-B7AC-43A8-A4AC-508ACE4A17C0Q38270332-18E95B0B-0912-4082-BC86-BA9F1BB2A591Q38335626-DC5D27A4-BBED-406F-ACEB-7372CD5F13FBQ38861678-048D6A76-F71E-4A0A-9A94-6224CC2994F9Q39020249-8CDD473F-959B-46F0-AEFD-B8C13C979322Q39173742-B608D148-ED40-45BE-8819-C98E0DA17212Q40312801-FF5A99F4-9DAD-490D-92E0-206AF9B35E16Q41195003-25726D6B-E6E7-4115-9271-17B2A9D17E3AQ41630808-D573DDD2-183C-49F1-B045-3068900DFC3BQ42143749-DA6C2D3D-C026-48DB-9FFB-4FC7701F0D29Q42634089-BF40FF1D-1589-4F88-B0E5-E261BDA1E89CQ46433404-D4A0A4F9-86DF-41C7-A4E8-A6AFE1C11740Q46924385-67DC8BDD-E789-4677-AABE-9B48F22955ADQ47835909-78946761-FD12-4F51-A002-43E682E23582Q48636743-3BBD3413-7BF9-41E5-9C5E-474362A84DDAQ50538898-BC7A0F1E-B5BB-4C15-87F0-FFC61B9D87BEQ51210259-0BDBBD47-6AE1-4B65-8764-BA7F79435AD8
P2860
Angiotensin II induces epithelial-to-mesenchymal transition in renal epithelial cells through reactive oxygen species/Src/caveolin-mediated activation of an epidermal growth factor receptor-extracellular signal-regulated kinase signaling pathway.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@ast
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@en
type
label
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@ast
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@en
prefLabel
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@ast
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@en
P2093
P2860
P356
P1476
Angiotensin II induces epithel ...... ated kinase signaling pathway.
@en
P2093
Jian-Kang Chen
Jianchun Chen
Raymond C Harris
P2860
P304
P356
10.1128/MCB.06410-11
P407
P577
2012-01-03T00:00:00Z