Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity.

Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity.

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http://www.wikidata.org/entity/Q35810948
Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhageHemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response.Haptoglobin Preserves Vascular Nitric Oxide Signaling during HemolysisNew insights into sickle cell disease: mechanisms and investigational therapies.Heme as a Target for Therapeutic Interventions.Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis.Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function.Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin.Determination of extinction coefficients of human hemoglobin in various redox states.Strong renal expression of heat shock protein 70, high mobility group box 1, inducible nitric oxide synthase, and nitrotyrosine in mice model of severe malaria.Haematoma scavenging in intracerebral haemorrhage: from mechanisms to the clinic.Phenotype-specific recombinant haptoglobin polymers co-expressed with C1r-like protein as optimized hemoglobin-binding therapeutics.Revisiting the putative role of heme as a trigger of inflammation.
P2860

Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity.

Item
http://www.wikidata.org/entity/Q35810948
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Different target specificities ...... vascular hemoglobin toxicity.
@ast
Different target specificities ...... vascular hemoglobin toxicity.
@en
type
label
Different target specificities ...... vascular hemoglobin toxicity.
@ast
Different target specificities ...... vascular hemoglobin toxicity.
@en
prefLabel
Different target specificities ...... vascular hemoglobin toxicity.
@ast
Different target specificities ...... vascular hemoglobin toxicity.
@en
P1433
P1476
P2093
P304
P31
P356
P478
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P5875
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Different target specificities ...... t vascular hemoglobin toxicity
@en
P2093
P304
P31
P356
10.1016/J.FREERADBIOMED.2015.09.016
P478
P50
P577
P5875
P698