HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis.
about
Friedreich's Ataxia: A Neuronal Point of View on the Oxidative Stress HypothesisIron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster deliveryDyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia.The diabetes drug target MitoNEET governs a novel trafficking pathway to rebuild an Fe-S cluster into cytosolic aconitase/iron regulatory protein 1Frataxin Is Localized to Both the Chloroplast and Mitochondrion and Is Involved in Chloroplast Fe-S Protein Function in ArabidopsisIron-sulfur cluster synthesis, iron homeostasis and oxidative stress in Friedreich ataxia.Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron-sulfur cluster enzyme activities and impaired iron homeostasis.Mammalian iron metabolism and its control by iron regulatory proteinsThe genetics of dystonias.Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexesMammalian Fe-S proteins: definition of a consensus motif recognized by the co-chaperone HSC20Fixing frataxin: 'ironing out' the metabolic defect in Friedreich's ataxiaMitochondrial pathophysiology in Friedreich's ataxia.Frataxin silencing inactivates mitochondrial Complex I in NSC34 motoneuronal cells and alters glutathione homeostasisA synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation.Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia.Protein networks in the maturation of human iron-sulfur proteins.Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts.Fe-S cluster assembly in the supergroup Excavata.Emerging therapeutics for the treatment of Friedreich’s ataxia
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P2860
HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@ast
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@en
type
label
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@ast
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@en
prefLabel
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@ast
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@en
P2860
P356
P1476
HSC20 interacts with frataxin ...... ogenesis and iron homeostasis.
@en
P2093
Gino Cortopassi
P2860
P304
P356
10.1093/HMG/DDR582
P577
2011-12-13T00:00:00Z