CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
about
Modulation of CD6 function through interaction with Galectin-1 and -3A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activationQuantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hubT Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex.T cell activation and differentiation is modulated by a CD6 domain 1 antibody ItolizumabCD6 as a therapeutic target in autoimmune diseases: successes and challenges.Fine mapping and functional analysis of the multiple sclerosis risk gene CD6The miR-155-PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiationStructures of CD6 and Its Ligand CD166 Give Insight into Their Interaction.The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1.CD6 modulates thymocyte selection and peripheral T cell homeostasisThe Scavenger Receptor SSc5D Physically Interacts with Bacteria through the SRCR-Containing N-Terminal DomainRelevance of CD6-Mediated Interactions in the Regulation of Peripheral T-Cell Responses and Tolerance.Response: Commentary: The Scavenger Receptor SSc5D Physically Interacts with Bacteria through the SRCR-Containing N-Terminal Domain.CD6 as a potential target for treating multiple sclerosisCD6 Receptor Regulates Intestinal Ischemia/Reperfusion-induced Injury by Modulating Natural IgM-producing B1a Cell Self-renewal.The anti-CD6 antibody itolizumab provides clinical benefit without lymphopenia in rheumatoid arthritis patients: results from a 6-month, open-label Phase I clinical trial.Bone Marrow Mesenchymal Stromal Cells Induce Proliferative, Cytokinic and Molecular Changes During the T Cell Response: The Importance of the IL-10/CD210 Axis.Rationale for treating primary Sjögren's syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab).Human treg cells are characterized by low/negative CD6 expressionBiophysical Characterization of CD6-TCR/CD3 Interplay in T CellsSmall RNAs detected in exosomes derived from the MH7A synovial fibroblast cell line with TNF-α stimulation
P2860
Q24299519-60F958E5-92CC-4972-9083-7541928E83ADQ28115070-D9885B1C-2A8B-4A20-B40D-26025D6055DFQ28771480-A1869AC4-F135-465B-AC76-BCCA07AA8439Q33715887-B6C3BAE3-9DAD-496F-A81E-AE8AC5988B2DQ33865748-47934B95-DA9E-4E8A-96AF-8D4538FB3FB0Q34337963-3733DEB9-1817-4D15-9896-6CCAD81502B2Q34701324-DB088622-C059-47B5-A059-B607546A4A73Q35307418-E83E4173-9137-4B17-A570-985610CA9F08Q35943010-4860697E-BE79-448F-B3DF-23FEB4D5D664Q37062264-4A58F8EA-743C-498F-B84C-0B4010D13805Q37179020-3413697E-0DD6-4008-BFD1-A638A3776DD5Q37334854-F84F4544-46E4-4D84-8669-F9271179421BQ38726869-27A298E4-A80F-4283-8892-16FCF6BBED87Q41526055-151DC296-57C9-4050-B7FB-98D33A577DA1Q42177117-8BD8FE14-A182-4DCE-8A7D-1EEAB9601FE0Q48023143-008AF2B0-A02E-4EB4-9A69-C4B2FC5B5C87Q48265755-1A315949-62D5-401B-BDDD-5CFF853117DFQ50628184-96946159-A71F-44EE-8ACA-8A4642FE1429Q51075376-0D83BD11-88F1-46FE-9CEB-EF3BB58371AAQ56896657-0A824BBB-31CF-4029-8F4B-703582846C03Q57816679-23F37C02-B686-4913-AC98-D75423F73B20Q58791358-0811D061-E81B-48ED-B97E-F647D34332FB
P2860
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@ast
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@en
type
label
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@ast
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@en
prefLabel
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@ast
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@en
P2093
P2860
P356
P1476
CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
@en
P2093
Alexandra Moreira
Alexandre M Carmo
Ana Mafalda Santos
Carine M Gonçalves
Georges Bismuth
Jane R Parnes
Mafalda Pinto
Marta I Oliveira
Mónica A A Castro
P2860
P304
P356
10.1002/EJI.201040528
P407
P577
2011-11-28T00:00:00Z