Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor. - Wikidata - wikimedia - TriplyDB

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor.

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor.

http://www.wikidata.org/entity/Q35819584

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Intermittent or sustained systemic inflammation and the preterm brain Caloric restriction suppresses microglial activation and prevents neuroapoptosis following cortical injury in rats PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier.Targeted Lipid Profiling Discovers Plasma Biomarkers of Acute Brain Injury The Controlled Cortical Impact Model: Applications, Considerations for Researchers, and Future Directions Pathophysiological links between traumatic brain injury and post-traumatic headaches CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced Neuroprotection Following Traumatic Brain Injury in Mice Glucocorticosteroids in nano-sterically stabilized liposomes are efficacious for elimination of the acute symptoms of experimental cerebral malaria PARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington's Disease A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury Alcohol exposure after mild focal traumatic brain injury impairs neurological recovery and exacerbates localized neuroinflammation.A data-driven approach for evaluating multi-modal therapy in traumatic brain injury.The relationship between serial [(18) F]PBR06 PET imaging of microglial activation and motor function following stroke in mice.COL-3, a chemically modified tetracycline, inhibits lipopolysaccharide-induced microglia activation and cytokine expression in the brain.Microglia regulate the number of neural precursor cells in the developing cerebral cortex.Delayed administration of alpha-difluoromethylornithine prevents hippocampus-dependent cognitive impairment after single and combined injury in mice.Effects of radiation combined injury on hippocampal function are modulated in mice deficient in chemokine receptor 2 (CCR2)PARP-1 modulates amyloid beta peptide-induced neuronal damage.Histological quantitation of brain injury using whole slide imaging: a pilot validation study in mice.Traumatic Brain Injury Increases Cortical Glutamate Network Activity by Compromising GABAergic Control Tibial fracture exacerbates traumatic brain injury outcomes and neuroinflammation in a novel mouse model of multitrauma.Osthole confers neuroprotection against cortical stab wound injury and attenuates secondary brain injury Rapamycin protects neurons from brain contusion‑induced inflammatory reaction via modulation of microglial activation Chronic Histopathological and Behavioral Outcomes of Experimental Traumatic Brain Injury in Adult Male Animals.New perspectives on central and peripheral immune responses to acute traumatic brain injury.Ginkgo biloba prevents transient global ischemia-induced delayed hippocampal neuronal death through antioxidant and anti-inflammatory mechanism.Activated microglia provide a neuroprotective role by balancing glial cell-line derived neurotrophic factor and tumor necrosis factor-α secretion after subacute cerebral ischemia.Microglia activation as a biomarker for traumatic brain injury Therapeutic applications of PARP inhibitors: anticancer therapy and beyond Arctigenin Treatment Protects against Brain Damage through an Anti-Inflammatory and Anti-Apoptotic Mechanism after Needle Insertion Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury.Etifoxine improves sensorimotor deficits and reduces glial activation, neuronal degeneration, and neuroinflammation in a rat model of traumatic brain injury.Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats.PARP-1 inhibition attenuates neuronal loss, microglia activation and neurological deficits after traumatic brain injury.Radiation exposure prior to traumatic brain injury induces responses that differ as a function of animal age.Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury.Protective effects of PARP inhibitor, PJ34, is related to down-regulation of calpain and NF-κB in a mouse model of TBI.A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats.MUTYH promotes oxidative microglial activation and inherited retinal degeneration.Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum.

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P2860

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor.

http://www.wikidata.org/entity/Q35819584

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Microglial activation induced ...... eatment with a PARP inhibitor.

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P2093

Deborah Bingham

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Jialing Liu

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Jian Shi

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Joana C d'Avila

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Raymond A Swanson

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Seok Joon Won

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Stephen Massa

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Tina I Lam

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P2860

Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

Rebound inflammation and the risk of ischemic stroke after discontinuation of aspirin therapy

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Microglia: a sensor for pathological events in the CNS

The vermicelli handling test: a simple quantitative measure of dexterous forepaw function in rats

Effect of acute poly(ADP-ribose) polymerase inhibition by 3-AB on blood-brain barrier permeability and edema formation after focal traumatic brain injury in rats.

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice

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10.1186/1742-2094-9-31

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9

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2012-02-15T00:00:00Z

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221833780

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1027611709

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22335939

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microglial inhibitor

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3298794

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