Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.
about
Unanticipated antigens: translation initiation at CUG with leucineIFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient responseNew Insights into the Function of the Immunoproteasome in Immune and Nonimmune CellsEndoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune responseMolecular architecture and assembly of the eukaryotic proteasomeBlm10 facilitates nuclear import of proteasome core particlesRegulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse developmentMelanoma immunotherapy using mature DCs expressing the constitutive proteasome.Immunoproteasome overexpression underlies the pathogenesis of thyroid oncocytes and primary hypothyroidism: studies in humans and mice.Induction of a chemoattractant transcriptional response by a Campylobacter jejuni boiled cell extract in colonocytes.Persistent hijacking of brain proteasomes in HIV-associated dementia.The synthesis of truncated polypeptides for immune surveillance and viral evasion.Proteasomal and lysosomal protein degradation and heart disease.The 20S proteasome splicing activity discovered by SpliceMet.Computational analysis and modeling of cleavage by the immunoproteasome and the constitutive proteasomeEpstein Barr virus-encoded EBNA1 interference with MHC class I antigen presentation reveals a close correlation between mRNA translation initiation and antigen presentation.Characterizing the specificity and cooperation of aminopeptidases in the cytosol and endoplasmic reticulum during MHC class I antigen presentationThe antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients.Subcellular antigen location influences T-cell activation during acute infection with Toxoplasma gondiiState of the art and challenges in sequence based T-cell epitope predictionHIV-1 envelope resistance to proteasomal cleavage: implications for vaccine induced immune responsesProteasome activator PA200 is required for normal spermatogenesis.Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses.Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells.Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation.Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in miceImmunoproteasome subunit LMP2 expression is deregulated in Sjogren's syndrome but not in other autoimmune disorders.Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.Post-proteasomal antigen processing for major histocompatibility complex class I presentation.Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophyUse of proteomics to define targets of T-cell immunity.Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.Dendritic cells, DRiPs, and DALIS in the control of antigen processing.Ubiquitin receptors and protein quality controlProteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liverThe design and implementation of the immune epitope database and analysis resource.
P2860
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P2860
Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Generation of major histocompa ...... between proteasomes and TPPII.
@ast
Generation of major histocompa ...... between proteasomes and TPPII.
@en
type
label
Generation of major histocompa ...... between proteasomes and TPPII.
@ast
Generation of major histocompa ...... between proteasomes and TPPII.
@en
prefLabel
Generation of major histocompa ...... between proteasomes and TPPII.
@ast
Generation of major histocompa ...... between proteasomes and TPPII.
@en
P2860
P356
P1433
P1476
Generation of major histocompa ...... between proteasomes and TPPII.
@en
P2093
Peter M Kloetzel
P2860
P304
P356
10.1038/NI1090
P407
P577
2004-07-01T00:00:00Z