Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).
about
Anti-beta2-glycoprotein I (beta2GPI) monoclonal antibodies with lupus anticoagulant-like activity enhance the beta2GPI binding to phospholipidsT cells that are autoreactive to beta2-glycoprotein I in patients with antiphospholipid syndrome and healthy individualsImmunologic and hematologic properties of antibodies to prothrombin and plasminogen in a mouse model.Hyperactivity in a mouse model of the antiphospholipid syndrome.Bacterial induction of autoantibodies to beta2-glycoprotein-I accounts for the infectious etiology of antiphospholipid syndrome.Chorea and high antiphospholipid antibodies: probable primary antiphospholipid syndrome.Activation of cultured vascular endothelial cells by antiphospholipid antibodies.The syndrome of thrombosis, thrombocytopenia, and recurrent spontaneous abortions associated with antiphospholipid antibodies: Hughes syndrome.Origin and pathogenesis of antiphospholipid antibodies.Preventing antiphospholipid antibody-induced fetal loss: a new ideaAssociation of anticardiolipin antibodies with vascular injury: possible mechanisms.The molecular basis of antiphospholipid syndrome.Pathophysiology of the antiphospholipid antibody syndrome.Significant changes in the levels of secreted cytokines in brains of experimental antiphospholipid syndrome miceMasking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice.Systemic exposure to irradiated apoptotic cells induces autoantibody production.Antiphospholipid antibodies: laboratory and pathogenetic aspects.Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.Anti-β2-glycoprotein I antibodies.MHC Class II Alleles influence Induction of Pathogenic Antiphospholipid Antibodies in a Thrombosis Mouse Model.Antibodies to cardiolipin and beta2-glycoprotein-1 in HTLV-1-associated myelopathy/tropical spastic paraparesis.Cryptic antiphospholipid autoantibodies and serum co-inhibitors.Beta 2-glycoprotein I.Anticardiolipin antibodies: specificity and function.Models for central nervous system complications of antiphospholipid syndrome.Antibodies to age-β2 glycoprotein I in patients with anti-phospholipid antibody syndrome.1996 diagnostic and classification criteria for the antiphospholipid/cofactors syndrome: a "mission impossible'?Genetic risk factors for aPL syndrome.In vivo models of thrombosis for the antiphospholipid syndrome.Immunomodulation of experimental APS: lessons from murine models.An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times.Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo.Intrauterine fetal death in mice caused by cytomegalovirus-derived peptide induced aPL antibodies.Thrombogenic properties of antiphospholipid antibodies do not depend on their binding to beta2 glycoprotein 1 (beta2GP1) alone.Antibodies to the atherosclerotic plaque components beta2-glycoprotein I and heat-shock proteins as risk factors for acute cerebral ischemia.Behavioral and cognitive deficits occur only after prolonged exposure of mice to antiphospholipid antibodies.Beta2GP-I in the anti phospholipid (Hughes') syndrome--from a cofactor to an autoantigen--from induction to prevention of antiphospholipid syndrome.
P2860
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P2860
Induction of antiphospholipid autoantibodies by immunization with beta 2 glycoprotein I (apolipoprotein H).
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@ast
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@en
type
label
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@ast
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@en
prefLabel
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@ast
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@en
P2093
P2860
P356
P1476
Induction of antiphospholipid ...... oprotein I (apolipoprotein H).
@en
P2093
P2860
P304
P356
10.1172/JCI115927
P407
P577
1992-09-01T00:00:00Z