MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF.
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Functional Role of Milk Fat Globule-Epidermal Growth Factor VIII in Macrophage-Mediated Inflammatory Responses and Inflammatory/Autoimmune DiseasesBiomarkers and molecular probes for cell death imaging and targeted therapeuticsImmunotherapy advances for glioblastomaAdjuvants for peptide-based cancer vaccinesImmunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translationPD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumorsIpilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: a randomized clinical trialEffect of granulocyte/macrophage colony-stimulating factor on circulating CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trialEmerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in OncologyNeuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE).Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction.Milk fat globule epidermal growth factor 8 attenuates acute lung injury in mice after intestinal ischemia and reperfusionImmunotherapy at large: Balancing tumor immunity and inflammatory pathologyRole of GM-CSF signaling in cell-based tumor immunization.IAP inhibitors enhance co-stimulation to promote tumor immunity.MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.MFG-E8 regulates the immunogenic potential of dendritic cells primed with necrotic cell-mediated inflammatory signalsMilk fat globule-EGF factor VIII in sepsis and ischemia-reperfusion injuryThe impact of MFG-E8 in chronic pancreatitis: potential for future immunotherapy?Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis.New blocking antibodies impede adhesion, migration and survival of ovarian cancer cells, highlighting MFGE8 as a potential therapeutic target of human ovarian carcinoma.A dual role for the immune response in a mouse model of inflammation-associated lung cancerLactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells.Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cellsPericyte-derived MFG-E8 regulates pathologic angiogenesisMalignant ovarian tumors with induced expression of carbonyl reductase show spontaneous regression.Biologic Activity of Autologous, Granulocyte-Macrophage Colony-Stimulating Factor Secreting Alveolar Soft-Part Sarcoma and Clear Cell Sarcoma VaccinesMolecular Mechanisms Underlying the Regulation of the MFG-E8 Gene Promoter Activity in Physiological and Inflammatory Conditions.Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophagesMilk fat globule-epidermal growth factor-factor 8 attenuates neutrophil infiltration in acute lung injury via modulation of CXCR2.Pathogenic mechanism of second hand smoke induced inflammation and COPD.Milk fat globule-epidermal growth factor-factor VIII downregulates interleukin-17 expression in sepsis by modulating STAT3 activation.Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients.Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction.MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injuryMultiple vaccinations: friend or foe.Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma.Concise Review: Mechanisms Behind Apoptotic Cell-Based Therapies Against Transplant Rejection and Graft versus Host Disease.The 'kiss of death' by dendritic cells to cancer cells.From regulation of dying cell engulfment to development of anti-cancer therapy.
P2860
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P2860
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@ast
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@en
type
label
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@ast
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@en
prefLabel
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@ast
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@en
P2093
P2860
P356
P1476
MFG-E8-mediated uptake of apop ...... ammatory activities of GM-CSF.
@en
P2093
Daniel R Carrasco
Glenn Dranoff
Martin Mihm
Masahisa Jinushi
Michael Dougan
Yukoh Nakazaki
P2860
P304
P356
10.1172/JCI30966
P407
P577
2007-07-01T00:00:00Z