Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine.
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Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatmentBiochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinasesHuman Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex FormationStructures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide bindingCrystal Structure of a Mammalian CTP: Phosphocholine Cytidylyltransferase Catalytic Domain Reveals Novel Active Site Residues within a Highly Conserved Nucleotidyltransferase FoldGenomics, evolution, and crystal structure of a new family of bacterial spore kinasesStructure of the Antibiotic Resistance Factor Spectinomycin Phosphotransferase from Legionella pneumophilaCrystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITYThe mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitorInsights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexesComparison of the cellular and biochemical properties of Plasmodium falciparum choline and ethanolamine kinasesHighly specific antibodies for co-detection of human choline kinase α1 and α2 isoformsPlasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite DeathFunctional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferationA novel small molecule antagonist of choline kinase-α that simultaneously suppresses MAPK and PI3K/AKT signalingStructural and enzymatic characterization of the choline kinase LicA from Streptococcus pneumoniaeCholine kinase alpha-Putting the ChoK-hold on tumor metabolism.Phosphorylation of Human Choline Kinase Beta by Protein Kinase A: Its Impact on Activity and Inhibition.Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line.Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling.Importance of Skin Changes in the Differential Diagnosis of Congenital Muscular Dystrophies.Structural modeling and biochemical characterization of recombinant KPN_02809, a zinc-dependent metalloprotease from Klebsiella pneumoniae MGH 78578.The hepatic circadian clock regulates the choline kinase α gene through the BMAL1-REV-ERBα axis.Design of symmetrical and nonsymmetrical N,N-dimethylaminopyridine derivatives as highly potent choline kinase alpha inhibitorsNew splicing mutation in the choline kinase beta (CHKB) gene causing a muscular dystrophy detected by whole-exome sequencing.Antiplasmodial activity and mechanism of action of RSM-932A, a promising synergistic inhibitor of Plasmodium falciparum choline kinase.1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety.Cho is phosphorylated to PCho by CHK dimer1H, 13C NMR studies of new 3-aminophenol isomers linked to pyridinium salts.
P2860
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P2860
Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@ast
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@en
type
label
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@ast
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@en
prefLabel
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@ast
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@en
P2093
P2860
P1476
Elucidation of human choline k ...... roducts ADP or phosphocholine.
@en
P2093
Arnon Lavie
Enrico Malito
Manfred Konrad
Wei Cun See Too
P2860
P304
P356
10.1016/J.JMB.2006.08.084
P407
P577
2006-09-03T00:00:00Z