Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts
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p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigenTransactivation of a ribosomal gene by simian virus 40 large-T antigen requires at least three activities of the protein.Cytotoxic T-lymphocyte epitope immunodominance in the control of choroid plexus tumors in simian virus 40 large T antigen transgenic mice.A truncated T antigen expressed from an alternatively spliced BK virus early mRNA.Regions and activities of simian virus 40 T antigen that cooperate with an activated ras oncogene in transforming primary rat embryo fibroblasts.T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisSimian virus 40 large T antigen and two independent T-antigen segments sensitize cells to apoptosis following genotoxic damageDifferential interaction of temperature-sensitive simian virus 40 T antigens with tumor suppressors pRb and p53A simian virus 40 large T-antigen segment containing amino acids 1 to 127 and expressed under the control of the rat elastase-1 promoter produces pancreatic acinar carcinomas in transgenic mice.Modification of a tumor antigen determinant to improve peptide/MHC stability is associated with increased immunogenicity and cross-priming a larger fraction of CD8+ T cellsThe amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.CD8+ T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40 T antigen-induced brain tumors.Anaplastic renal carcinoma expressing SV40 T antigen in a female TRAMP mouse.The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP.pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppressionSimian virus 40 large T antigen J domain and Rb-binding motif are sufficient to block apoptosis induced by growth factor withdrawal in a neural stem cell line.Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.Transcriptional control of SV40 T-antigen expression allows a complete reversion of immortalization.Transactivation of E2F-regulated genes by polyomavirus large T antigen: evidence for a two-step mechanism.ETS-1 and ETS-2 are upregulated in a transgenic mouse model of pigmented ocular neoplasm.A structure-guided mutational analysis of simian virus 40 large T antigen: identification of surface residues required for viral replication and transformation.
P2860
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P2860
Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts
description
1995 nî lūn-bûn
@nan
1995年の論文
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1995年論文
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1995年論文
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1995年論文
@zh-hk
1995年論文
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1995年論文
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1995年论文
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1995年论文
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1995年论文
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name
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@ast
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@en
type
label
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@ast
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@en
prefLabel
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@ast
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@en
P2093
P2860
P1433
P1476
Simian virus 40 large T antige ...... ansform rat embryo fibroblasts
@en
P2093
P2860
P304
P407
P577
1995-02-01T00:00:00Z