The mitochondrial death pathway: a promising therapeutic target in diseases - Wikidata - wikimedia - TriplyDB

The mitochondrial death pathway: a promising therapeutic target in diseases

The mitochondrial death pathway: a promising therapeutic target in diseases

http://www.wikidata.org/entity/Q35831981

about

HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction β-elemene effectively suppresses the growth and survival of both platinum-sensitive and -resistant ovarian tumor cells Direct Activation of Bax Protein for Cancer Therapy Antitumor peptides from marine organisms Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization.LFG-500, a newly synthesized flavonoid, induces apoptosis in human ovarian carcinoma SKOV3 cells with involvement of the reactive oxygen species-mitochondria pathway Grifolin induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways.Effect of nitric oxide on mitochondrial activity of human synovial cells.ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.Ageing is a risk factor in imatinib mesylate cardiotoxicity A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes.Molecular mechanisms of 3,3'-dichlorobenzidine-mediated toxicity in HepG2 cells.Calycosin suppresses breast cancer cell growth via ERβ-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways.Chemistry and biology of the caged Garcinia xanthones.Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1).MicroRNA-345 induces apoptosis in pancreatic cancer cells through potentiation of caspase-dependent and -independent pathways.TAT Modification of Alpha-Helical Anticancer Peptides to Improve Specificity and Efficacy Garcinia dulcis Fruit Extract Induced Cytotoxicity and Apoptosis in HepG2 Liver Cancer Cell Line.Apoptosis Activation in Human Lung Cancer Cell Lines by a Novel Synthetic Peptide Derived from Conus californicus Venom.Apoptotic and anti-metastatic effects of the whole skin of Venenum bufonis in A549 human lung cancer cells.Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65.Procaspase-9 induces its cleavage by transnitrosylating XIAP via the Thioredoxin system during cerebral ischemia-reperfusion in rats.Mechanisms of mitochondrial damage in keratinocytes by pemphigus vulgaris antibodies.Inhibitory effect of bufalin on retinoblastoma cells (HXO-RB44) via the independent mitochondrial and death receptor pathway.HIV-1 promonocytic and lymphoid cell lines: an in vitro model of in vivo mitochondrial and apoptotic lesion.Expressing and functional analysis of mammalian apoptotic regulators in yeast.Basic mechanisms of neurodegeneration: a critical update.Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models.Cell death controlling complexes and their potential therapeutic role.The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update.Comparison of cell cycle components, apoptosis and cytoskeleton-related molecules and therapeutic effects of flavopiridol and geldanamycin on the mouse fibroblast, lung cancer and embryonic stem cells.Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics.Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells.Butein Shows Cytotoxic Effects and Induces Apoptosis in Human Ovarian Cancer Cells.Anticarcinogenic effects of the ethanolic extract of Salix aegyptiaca in colon cancer cells: involvement of Akt/PKB and MAPK pathways.Microarray determination of Bcl-2 family protein inhibition sensitivity in breast cancer cells.The proteasome inhibitor lactacystin exerts its therapeutic effects on glioma via apoptosis: an in vitro and in vivo study.Induction of apoptosis by a potent caffeic acid derivative, caffeic acid undecyl ester, is mediated by mitochondrial damage in NALM-6 human B cell leukemia cells.Neuroglobin and friends.Hypersensitivity of mtDNA-depleted cells to staurosporine-induced apoptosis: roles of Bcl-2 downregulation and cathepsin B.

P2860

Q21145793-33E1FB22-18A9-434E-A659-8F821164B5C9 Q28387031-42064800-3BC0-45BF-A50C-F5E9583FE7E9 Q30353924-E8B98464-7413-49EF-A702-2303602BC1C8 Q31040702-539BC54E-03FB-4D31-B614-8845F47ECBF3 Q33651806-DEF354C6-4994-46BD-9C41-60ACDEF79982 Q33744850-A3088A04-B43A-4373-A4B6-84022CA2754B Q33750839-5BD6EB29-0927-4A62-B27E-6C6D7625982A Q33814899-F67B0744-A2F4-4E48-913F-AF66D39C3BF8 Q33980322-D800A8A7-BC97-4083-B9C2-4359532C881A Q34548719-E66BCD98-BEF5-49B2-AF42-BDD815D40D22 Q34746484-ECFE36C2-2504-4368-A223-BE6F33419F22 Q35113557-F32A3A07-CD0C-43E3-8D8E-9D5DC8A75989 Q35117885-62E11A4F-6CCE-482A-BB47-722332F3B60C Q35129332-4C9836DC-D372-4590-AC24-0FEDE5E2FAF5 Q35718966-7D8D8AF5-B9A2-4371-8630-BFCDA1D89228 Q35738711-72E1791F-826F-4A8A-A081-24A5E8C84303 Q35787581-E6F33E7E-E788-4490-9D19-C6FFC674CBE4 Q36236370-8EF5B9C8-8969-4C37-9B98-80852D47C15F Q36638317-F0867718-5D2B-4D1A-8285-7C959628A038 Q36645684-9AE13E30-5EAA-4BF0-869C-AAAA346EA2FC Q36744894-F6612930-B955-4B8F-AB6B-2D1950A99A03 Q36774130-B2305CE8-3E6A-49FC-B49E-606B5F66B54E Q36910181-D9912272-545A-4739-B151-A5CE1870D57A Q37448208-1EA09B6C-2CD7-45E5-A16C-5A2000506C64 Q37604361-6B97F688-39D6-4C80-B26D-721309D41078 Q37632266-5D189269-D786-4726-A9F1-BE7CB582618E Q37673274-4A22DA61-4053-4293-8251-8A683AAFFF5E Q37696104-CF1683C2-44A2-41A1-9FAB-DBDCCC762A69 Q38260863-F98FE26E-FC72-4718-B3D3-A531C46E0AF8 Q38331196-436F642D-C7E9-432B-ACB6-955315160C69 Q38737004-25848207-BDBD-491F-9057-E83D446779FE Q38750384-CCE6EE7F-3DA7-4F89-889C-DD14C6E1BBB9 Q38811039-D436C524-508F-46D4-A23E-7774C604D1BF Q38859153-BCEF1D9D-4792-4C05-9A76-2284EFFECEFF Q39069150-4BF730DB-F273-4CB6-B4E7-A2D6DF16B43C Q39168078-879053A6-9FD6-447B-9B41-5AA9D972B364 Q39169079-61BE0CDE-9140-4BD0-A6E5-4BD269D71AB0 Q39228259-5DF71FFB-B833-4885-8A4F-CD1111310D95 Q39434576-7BD2435F-5A3B-44AA-B568-C143B2EF7572 Q39633395-B532E669-A9AF-4A2F-9DAE-A6D828AFEFA3

P2860

The mitochondrial death pathway: a promising therapeutic target in diseases

http://www.wikidata.org/entity/Q35831981

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

2009年论文

@zh

2009年论文

@zh-cn

name

The mitochondrial death pathway: a promising therapeutic target in diseases

@ast

The mitochondrial death pathway: a promising therapeutic target in diseases

@en

type

label

The mitochondrial death pathway: a promising therapeutic target in diseases

@ast

The mitochondrial death pathway: a promising therapeutic target in diseases

@en

prefLabel

The mitochondrial death pathway: a promising therapeutic target in diseases

@ast

The mitochondrial death pathway: a promising therapeutic target in diseases

@en

P1433

Q35831981-E14431CB-9C79-4049-8A49-4D3BD550A9AA

P1476

Q35831981-20FCE2D2-8AE8-4586-9304-1CE464320F74

P2093

Q35831981-0C664D09-477C-4FFE-A005-A014655325E1

Q35831981-35CB9D6A-D511-4C03-8A8A-B2C371CD6009

Q35831981-4F8E21B4-C798-49E7-B64B-E2E0A4F01471

Q35831981-9EAD9A86-AE39-466C-9507-9F9AE87FCCFD

P2860

Q35831981-04684829-589E-42D3-879C-8F6988141DB7

Q35831981-0560134B-DD26-48DF-8F00-1978BEF8A65C

Q35831981-061EB529-B6A9-47A6-A7DB-5C345B6E791A

Q35831981-095524BB-EF9B-470D-B25C-65A6857B94B4

Q35831981-0C1F276C-6DD5-4045-919E-2303D5DE37B7

Q35831981-0CA6F2BA-5962-4C72-A090-96DF5C4F894F

Q35831981-0E0CE596-9AD7-43ED-8010-EF3A02221B94

Q35831981-0EFBBF17-9580-4E8C-AA2B-6459E17AC7F1

Q35831981-111BE4D0-AC71-4FC6-A4C4-0AD1FE2983DC

Q35831981-118AB717-673A-499D-B5C3-0230F95D3B6F

P304

Q35831981-15D1797D-AA6B-4539-88A1-65C4B3970DFE

P31

Q35831981-784636C7-82A3-483D-8DA3-4B39BD38551E

Q35831981-7BF4EDDD-D906-463D-9BCE-A74E7DCCAE3C

P356

Q35831981-8456A97D-DC48-4361-9A0C-50279D6D9657

P433

Q35831981-37E881AA-3473-44B0-87B4-B13DC0DF61C2

P478

Q35831981-739C8080-7111-4950-9558-BB5EFC4AA5BF

P577

Q35831981-77361E70-2625-4E2F-88CE-475EBD8DE839

Q35831981-B5B2FD20-BC2B-4DAF-A53A-E24E4997CFD8

P5875

Q35831981-AE6023C4-FFEF-4E7A-B918-BA955574D695

P698

Q35831981-9EC1489E-E9E2-4E09-8301-E6234FE7B67E

P921

Q35831981-42C98AAA-985D-4A2E-B701-780818DEB5D8

Q35831981-74A530A0-80EA-4DC2-8ACC-041C59D6CE78

P932

Q35831981-304913D8-B590-4483-9938-64C9F7166A96

P356

J.1582-4934.2009.00697.X

P1433

Journal of Cellular and Molecular Medicine

P1476

The mitochondrial death pathway: a promising therapeutic target in diseases

@en

P2093

Bertrand Joseph

http://www.w3.org/2001/XMLSchema#string

Eva Szegezdi

http://www.w3.org/2001/XMLSchema#string

George E N Kass

http://www.w3.org/2001/XMLSchema#string

Sanjeev Gupta

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular characterization of mitochondrial apoptosis-inducing factor

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

PUMA, a novel proapoptotic gene, is induced by p53

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

Caspase-10 is an initiator caspase in death receptor signaling

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

Mechanism of XIAP-mediated inhibition of caspase-9

P304

1004-1033

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1111/J.1582-4934.2009.00697.X

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P577

2009-02-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

2009-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24018662

http://www.w3.org/2001/XMLSchema#string

P698

19220575

http://www.w3.org/2001/XMLSchema#string

P921

physiological phenomena

P932

4496101

http://www.w3.org/2001/XMLSchema#string