A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis.
about
Natural Products for Chemoprevention of Breast CancerThe traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology.Recent studies on ursolic acid and its biological and pharmacological activity.Warfarin and coumarin-like Murraya paniculata extract down-regulate EpCAM-mediated cell adhesion: individual components versus mixture for studying botanical metastatic chemopreventivesUrsolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.The paradigm-shifting idea and its practice: from traditional abortion Chinese medicine Murraya paniculata to safe and effective cancer metastatic chemopreventives.A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatmentHypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid's anti-metastatic effect in 4T1 tumor bearing miceEffects of Abies sibirica terpenes on cancer- and aging-associated pathways in human cells.A smart pH-responsive nano-carrier as a drug delivery system for the targeted delivery of ursolic acid: suppresses cancer growth and metastasis by modulating P53/MMP-9/PTEN/CD44 mediated multiple signaling pathways.Comparative proteomics-network analysis of proteins responsible for ursolic acid-induced cytotoxicity in colorectal cancer cells.Combined Use of Zoledronic Acid Augments Ursolic Acid-Induced Apoptosis in Human Osteosarcoma Cells through Enhanced Oxidative Stress and Autophagy.The Apoptotic Effect of Ursolic Acid on SK-Hep-1 Cells is Regulated by the PI3K/Akt, p38 and JNK MAPK Signaling Pathways.Synthesis, Characterization, and Anticancer Activity of Novel Lipophilic Emodin Cationic Derivatives.Anti-hepatocellular carcinoma activity and mechanism of chemopreventive compounds: ursolic acid derivatives.The Architecture and Function of Monoclonal Antibody-Functionalized Mesoporous Silica Nanoparticles Loaded with Mifepristone: Repurposing Abortifacient for Cancer Metastatic Chemoprevention.Metapristone (RU486 metabolite) suppresses NSCLC by targeting EGFR-mediated PI3K/AKT pathway.Ursolic acid enhances the therapeutic effects of oxaliplatin in colorectal cancer by inhibition of drug resistance.
P2860
Q26770555-E39EBD96-0AD8-4CEE-ABFB-EE31773297C0Q33819016-F3DC1D33-0BEA-463F-A63C-23876948DF82Q36920683-5CEA6E08-AC69-495F-B4CF-E08BD5077512Q37144935-E5126FE7-2534-4A5B-8242-E7F27DFB4A84Q37165886-5E761D51-2EB0-49C5-902B-C1885B0BEFFFQ37225376-5E729989-9276-4AD9-B876-2733504CE138Q37687351-23EB7E47-455B-4FC3-AF6E-8BE62C976A7BQ37687717-6069478E-45C2-4AC6-BD27-BBF231485588Q37696371-BE3D6502-8C96-4E06-859C-7EAD94C6F162Q38702941-C03559C7-9A16-45F2-891B-13055E232B87Q38710255-CC1049E8-4FFB-410C-8371-C6AB359A9A01Q38727632-83827578-B8C7-4881-BA33-AF84870AA2CCQ38776270-632EFFB7-C3F9-4FBF-B760-C4E97DCDE3B6Q38860481-4AEE05B0-AA78-4E0B-AEBC-42A8086F51BAQ39450856-3F8A9DA2-252C-4325-8DCA-C62423EBA589Q39878482-87DA206A-D846-4658-A82A-6730EFFEDAC5Q43987893-495D2D1E-5B75-4823-9DF3-51CA308205E3Q46284958-1A32430F-E3FC-4B26-B2FB-CEACD9BFC4D2
P2860
A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A pentacyclic triterpene natur ...... and prevent cancer metastasis.
@ast
A pentacyclic triterpene natur ...... and prevent cancer metastasis.
@en
type
label
A pentacyclic triterpene natur ...... and prevent cancer metastasis.
@ast
A pentacyclic triterpene natur ...... and prevent cancer metastasis.
@en
prefLabel
A pentacyclic triterpene natur ...... and prevent cancer metastasis.
@ast
A pentacyclic triterpene natur ...... and prevent cancer metastasis.
@en
P2093
P2860
P356
P1433
P1476
A pentacyclic triterpene natur ...... and prevent cancer metastasis
@en
P2093
Jianzhong Chen
Jingwei Shao
Liping Xiang
Rodney J Y Ho
Xiang Yang
Xiufen Chen
P2860
P304
P356
10.18632/ONCOTARGET.3261
P407
P577
2015-04-01T00:00:00Z