Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I.
about
The recruitment of RNA polymerase I on rDNA is mediated by the interaction of the A43 subunit with Rrn3Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBFIsolation and analysis of the fission yeast gene encoding polymerase delta accessory protein PCNA.A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system.The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter.A novel RNA polymerase I transcription initiation factor, TIF-IE, commits rRNA genes by interaction with TIF-IB, not by DNA binding.The DNA supercoiling architecture induced by the transcription factor xUBF requires three of its five HMG-boxesA TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase IxUBF and Rib 1 are both required for formation of a stable polymerase I promoter complex in X. laevisFactor C*, the specific initiation component of the mouse RNA polymerase I holoenzyme, is inactivated early in the transcription processDual role of the nucleolar transcription factor UBF: trans-activator and antirepressor.Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophyThe HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase IDimerization and HMG box domains 1-3 present in Xenopus UBF are sufficient for its role in transcriptional enhancement.HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF.Presence of an inhibitor of RNA polymerase I mediated transcription in extracts from growth arrested mouse cells.The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription.Variants of the Xenopus laevis ribosomal transcription factor xUBF are developmentally regulated by differential splicingThe yeast RNA polymerase I promoter: ribosomal DNA sequences involved in transcription initiation and complex formation in vitroIdentification of a sequence-specific protein binding the 5'-transcribed spacer of rat ribosomal genes.The RNA polymerase I transcription factor xUBF contains 5 tandemly repeated HMG homology boxes.Complex formation of nuclear proteins with the RNA polymerase I promoter and repeated elements in the external transcribed spacer of Cucumis sativus ribosomal DNA.Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity.Recognition of the Xenopus ribosomal core promoter by the transcription factor xUBF involves multiple HMG box domains and leads to an xUBF interdomain interaction.A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesisThe nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation.DNA sequence encoded repression of rRNA gene transcription in chromatin.TTF-I determines the chromatin architecture of the active rDNA promoter.
P2860
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P2860
Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@ast
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@en
type
label
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@ast
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@en
prefLabel
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@ast
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@en
P2093
P2860
P356
P1476
Isolation and functional chara ...... ity to mouse RNA polymerase I.
@en
P2093
P2860
P304
P356
10.1093/NAR/18.6.1385
P407
P577
1990-03-01T00:00:00Z