Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival.
about
NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingThe nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processingNucleophosmin (NPM1/B23) interacts with activating transcription factor 5 (ATF5) protein and promotes proteasome- and caspase-dependent ATF5 degradation in hepatocellular carcinoma cellsNuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survivalNucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteasesInsights into the regulation of neuronal viability by nucleophosmin/B23Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival, and is Involved in PEDV GrowthEbp1 sumoylation, regulated by TLS/FUS E3 ligase, is required for its anti-proliferative activity.The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cellsRegulation of nucleolus assembly by non-coding RNA polymerase II transcriptsNucleolin and nucleophosmin: nucleolar proteins with multiple functions in DNA repair.Neuroprotection signaling of nuclear akt in neuronal cellsSUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2Dephosphorylation of nucleophosmin by PP1β facilitates pRB binding and consequent E2F1-dependent DNA repairIdentification of proteins differentially expressed in adriamycin-resistant (pumc-91/ADM) and parental (pumc-91) human bladder cancer cell lines by proteome analysis.A redox mechanism underlying nucleolar stress sensing by nucleophosminDissecting the cell to nucleus, perinucleus and cytosol.An extensive tumor array analysis supports tumor suppressive role for nucleophosmin in breast cancerTRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome AmplificationHIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype.Nucleophosmin, a critical Bax cofactor in ischemia-induced cell deathNucleolar targeting: the hub of the matter.The promiscuity of ARF interactions with the proteasome.Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.Intrinsically disordered regions of nucleophosmin/B23 regulate its RNA binding activity through their inter- and intra-molecular association.Nucleophosmin mutations in acute myeloid leukemia: a tale of protein unfolding and mislocalization.Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites.Biological and clinical consequences of NPM1 mutations in AML.Estrogen stimulates the proliferation of human endometrial cancer cells by stabilizing nucleophosmin/B23 (NPM/B23).Human papillomavirus type 16 E6/E7 upregulation of nucleophosmin is important for proliferation and inhibition of differentiation.Protein SUMOylation is Involved in Cell-cycle Progression and Cell Morphology in Giardia lamblia.S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1-GAPDH death cascade.Nol12 is a multifunctional RNA binding protein at the nexus of RNA and DNA metabolism.Lysine 263 residue of NPM/B23 is essential for regulating ATP binding and B23 stability.Ebp1 association with nucleophosmin/B23 is essential for regulating cell proliferation and suppressing apoptosis.SUMOylation of NPM1 with SUMO1SUMOylation of NPM1 with SUMO2;3
P2860
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P2860
Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@ast
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@en
type
label
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@ast
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@en
prefLabel
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@ast
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@en
P2093
P2860
P356
P1476
Sumoylation of nucleophosmin/B ...... ll proliferation and survival.
@en
P2093
Kazuya Shinmura
Kenji Fukasawa
Keqiang Ye
Shaozhong Dong
Sumin Kang
Sung-Wuk Jang
Zhixue Liu
Zhiyong Ma
P2860
P304
P356
10.1073/PNAS.0701806104
P407
P577
2007-05-29T00:00:00Z