Monoclonal antibodies to Alzheimer neurofibrillary tangles. 1. Identification of polypeptides.
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Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer diseaseTau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse modelExpression in cultured human neuroblastoma cells of epitopes associated with affected neurons in Alzheimer's disease.Ubiquitin and microtubule-associated protein tau immunoreactivity each define distinct structures with differing distributions and solubility properties in Alzheimer brain.A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis.Pronounced microgliosis and neurodegeneration in aged rats after tau gene transferTau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat.Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.Astrocytes and microglia in human brain share an epitope recognized by a B-lymphocyte-specific monoclonal antibody (LN-1).Frontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus.Pathological characterization of astrocytic hyaline inclusions in familial amyotrophic lateral sclerosis.Detection of HLA-DR on microglia in the human brain is a function of both clinical and technical factorsAlzheimer's disease. A double-labeling immunohistochemical study of senile plaques.Immune electron microscopic characterization of monoclonal antibodies to Alzheimer neurofibrillary tangles.Characteristics of TBS-extractable hyperphosphorylated tau species: aggregation intermediates in rTg4510 mouse brain.Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical methodAlzheimer's neurofibrillary tangles contain unique epitopes and epitopes in common with the heat-stable microtubule associated proteins tau and MAP2.
P2860
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P2860
Monoclonal antibodies to Alzheimer neurofibrillary tangles. 1. Identification of polypeptides.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Monoclonal antibodies to Alzhe ...... dentification of polypeptides.
@ast
Monoclonal antibodies to Alzhe ...... dentification of polypeptides.
@en
type
label
Monoclonal antibodies to Alzhe ...... dentification of polypeptides.
@ast
Monoclonal antibodies to Alzhe ...... dentification of polypeptides.
@en
prefLabel
Monoclonal antibodies to Alzhe ...... dentification of polypeptides.
@ast
Monoclonal antibodies to Alzhe ...... dentification of polypeptides.
@en
P2093
P2860
P1476
Monoclonal antibodies to Alzhe ...... Identification of polypeptides
@en
P2093
P2860
P304
P407
P577
1985-08-01T00:00:00Z