Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation
about
Viral hepatitis and hepatocellular carcinomaHuman immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.The enigmatic X gene of hepatitis B virusProteasome complex as a potential cellular target of hepatitis B virus X proteinHepatocellular carcinoma: Epidemiology, risk factors and pathogenesisThe hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosisA direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein geneInvolvement of DNA damage response pathways in hepatocellular carcinoma.Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex.Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion methodVirus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma.Hepatitis B virus HBx protein deregulates cell cycle checkpoint controlsHepatitis B virus X protein interferes with cellular DNA repair.Identification of positive and negative regulatory regions involved in regulating expression of the human cytomegalovirus UL94 late promoter: role of IE2-86 and cellular p53 in mediating negative regulatory function.Phosphorylation of p53: a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells.Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.The Increased Level of Serum p53 in Hepatitis B-Associated Liver CirrhosisAltered proteolysis and global gene expression in hepatitis B virus X transgenic mouse liver.pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutantsHepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma.Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells.Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutantsX-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo.The hepatitis B virus X gene induces p53-mediated programmed cell death.Construction of eukaryotic expression vector of HBV x gene.Altered binding site selection of p53 transcription cassettes by hepatitis B virus X proteinActivation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to RasThe hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors.Hepatocyte Factor JMJD5 Regulates Hepatitis B Virus Replication through Interaction with HBxAn overview of molecular epidemiology of hepatitis B virus (HBV) in IndiaInducible nitric oxide synthase expression in chronic viral hepatitis. Evidence for a virus-induced gene upregulation.Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner.Association study between mannose-binding lectin haplotypes and X gene mutation of hepatitis B virus from treatment naïve patients.Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal.Effect of Hepatitis B Virus X Gene on the Expression Level of p53 Gene using Hep G2 Cell Line.A Role for the Host DNA Damage Response in Hepatitis B Virus cccDNA Formation-and Beyond?Stochastic and Deterministic Models of Cellular p53 Regulation.Hepatitis B virus pX targets TFIIB in transcription coactivation.Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis, and is blocked by insulin-like growth factor II.Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein.
P2860
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P2860
Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Direct interaction of the hepa ...... ement-directed transactivation
@ast
Direct interaction of the hepa ...... ement-directed transactivation
@en
type
label
Direct interaction of the hepa ...... ement-directed transactivation
@ast
Direct interaction of the hepa ...... ement-directed transactivation
@en
prefLabel
Direct interaction of the hepa ...... ement-directed transactivation
@ast
Direct interaction of the hepa ...... ement-directed transactivation
@en
P2093
P2860
P1433
P1476
Direct interaction of the hepa ...... ement-directed transactivation
@en
P2093
Antunovic J
Cromlish JA
Greenblatt J
P2860
P304
P407
P577
1995-03-01T00:00:00Z