KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
about
Cell biology and genetics of minimal change diseasePodocytesMutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndromeEvolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular developmentGenetic testing in steroid-resistant nephrotic syndrome: when and how?Exploring the genetic basis of early-onset chronic kidney disease.NPHS2 mutations account for only 15% of nephrotic syndrome cases.FAT1 mutations cause a glomerulotubular nephropathyA small molecule screening to detect potential therapeutic targets in human podocytes.A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis.The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.Overgrazing induces alterations in the hepatic proteome of sheep (Ovis aries): an iTRAQ-based quantitative proteomic analysis.Recent advances in understanding and treating nephrotic syndrome.Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency.Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy.Clinical genetic testing using a custom-designed steroid-resistant nephrotic syndrome gene panel: analysis and recommendations.Stressed podocytes-mechanical forces, sensors, signaling and response.Whole exome sequencing: a state-of-the-art approach for defining (and exploring!) genetic landscapes in pediatric nephrology.Genetics of childhood steroid-sensitive nephrotic syndrome.Podocyte-actin dynamics in health and disease.Integrin-mediated mechanotransduction.The genetic basis of cerebral palsy.MAGI2 Mutations Cause Congenital Nephrotic Syndrome.New Insights into Podocyte Biology in Glomerular Health and Disease.Drosophila Malpighian Tubules: A Model for Understanding Kidney Development, Function, and Disease.Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation.Steroid receptor co-activator interacting protein (SIP) mediates EGF-stimulated expression of the prostaglandin synthase COX2 and prostaglandin release in human myometrium.Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.NPHS2 Mutations: A Closer Look to Latin American Countries.Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome.A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation.APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death.Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte.Using the Drosophila Nephrocyte to Model Podocyte Function and Disease.Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.Genetic testing in steroid-resistant nephrotic syndrome: why, who, when and how?Structural analyses of key features in the KANK1·KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex.A novel HIF1AN substrate KANK3 plays a tumor-suppressive role in hepatocellular carcinoma.
P2860
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P2860
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@ast
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@en
type
label
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@ast
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@en
prefLabel
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@ast
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@en
P2093
P2860
P50
P921
P356
P1476
KANK deficiency leads to podocyte dysfunction and nephrotic syndrome.
@en
P2093
Andrej Boor
Carolin E Sadowski
Friedhelm Hildebrandt
Fujian Zhang
Henry Fehrenbach
Heon Yung Gee
Humphrey Fang
Jeffrey W Innis
Joseph Washburn
Julia Hoefele
P2860
P304
P356
10.1172/JCI79504
P407
P577
2015-05-11T00:00:00Z