Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus. - Wikidata - wikimedia - TriplyDB

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

http://www.wikidata.org/entity/Q35840762

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The Role of γδ T Cells in Systemic Lupus Erythematosus Epstein-Barr virus in systemic lupus erythematosus, rheumatoid arthritis and multiple sclerosis—association and causation Modulatory function of invariant natural killer T cells in systemic lupus erythematosus Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12 Response to ‘T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?’Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).Altered B cell signalling in autoimmunity.Immune activation is associated with CD8 T cell interleukin-21 production in HIV-1-infected individuals.Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus Inhibition of aberrant circulating Tfh cell proportions by corticosteroids in patients with systemic lupus erythematosus.Interleukin (IL)-21 promotes intestinal IgA response to microbiota.Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus.Autoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosus Increased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus.IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms.Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: preliminary findings.Hyperactivation and in situ recruitment of inflammatory Vδ2 T cells contributes to disease pathogenesis in systemic lupus erythematosus.pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood.Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage.Insights into the role of follicular helper T cells in autoimmunity.B-cell targeted therapeutics in clinical development.Human T follicular helper (Tfh) cells and disease.Interleukin-17 in systemic lupus erythematosus: A comprehensive review.Follicular helper T cell in immunity and autoimmunity The Role of STAT Signaling Pathways in the Pathogenesis of Systemic Lupus Erythematosus.T follicular helper cells, interleukin-21 and systemic lupus erythematosus.Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses.Toll-like receptor 9 activation enhances B cell activating factor and interleukin-21 induced anti-proteinase 3 autoantibody production in vitro.Involvement of interleukin-21 in the pathophysiology of aplastic anemia.Upregulation of Interleukin 21 and Interleukin 21 Receptor in Patients with Dermatomyositis and Polymyositis.IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells Interleukin-21, a potential diagnostic and therapeutic target for systemic lupus erythematosus.Blockade of Treg Cell Differentiation and Function by the Interleukin-21-Mechanistic Target of Rapamycin Axis Via Suppression of Autophagy in Patients With Systemic Lupus Erythematosus.CTL-Promoting Effects of IL-21 Counteract Murine Lupus in the Parent→F1 Graft-versus-Host Disease Model.Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21(+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis.Increased IL-17 and IL-21 producing TCRαβ+CD4-CD8- T cells in Chinese systemic lupus erythematosus patients.Oestrogen up-regulates interleukin-21 production by CD4(+) T lymphocytes in patients with systemic lupus erythematosus.Down-regulation of expression of retinoid acid-related orphan receptor C (RORC) in systemic lupus erythematosus.Circulating CXCR5+CD4+helper T cells in systemic lupus erythematosus patients share phenotypic properties with germinal center follicular helper T cells and promote antibody production.

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Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

http://www.wikidata.org/entity/Q35840762

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

@zh-cn

name

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

@ast

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

@en

type

label

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

@ast

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

@en

prefLabel

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

@ast

Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

@en

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Arthritis Research and Therapy

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Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus.

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Berber Doornbos-van der Meer

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Johanna Westra

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Marc Bijl

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Pieter C Limburg

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Sebastian Dolff

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Wayel H Abdulahad

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P2860

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3

A critical role for IL-21 in regulating immunoglobulin production

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

Elevated interleukin-21 correlated to Th17 and Th1 cells in patients with immune thrombocytopenia.

IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation.

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10.1186/AR3474

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5

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Cees G M Kallenberg

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2011-09-29T00:00:00Z

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51681268

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