Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease. - Wikidata - wikimedia - TriplyDB

Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease.

Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease.

http://www.wikidata.org/entity/Q35840797

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The Newly Identified T Helper 22 Cells Lodge in Leukemia Gene expression profiling offers insights into the role of innate immune signaling in SSc High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis.Th17 Cells Coordinate with Th22 Cells in Maintaining Homeostasis of Intestinal Tissues and both are Depleted in SIV-Infected Macaques.Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction.Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts.IL-17A induces endothelial inflammation in systemic sclerosis via the ERK signaling pathway Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?Expression profiling. Combinatorial labeling of single cells for gene expression cytometry.CD26 Expression on T Helper Populations and sCD26 Serum Levels in Patients with Rheumatoid Arthritis.The Role of IL-17 and Th17 Lymphocytes in Autoimmune Diseases Increased expressions of IL-22 and Th22 cells in the coxsackievirus B3-Induced mice acute viral myocarditis.Frequency of circulating topoisomerase-I-specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma Elevated frequencies of circulating Th22 cell in addition to Th17 cell and Th17/Th1 cell in patients with acute coronary syndrome.Circulating Th22 and Th9 levels in patients with acute coronary syndrome.TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients.Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts.Increased frequency of Th17 cells in systemic sclerosis is related to disease activity and collagen overproduction.Circulating biomarkers of interstitial lung disease in systemic sclerosis.Th22 and related cytokines in inflammatory and autoimmune diseases.Therapeutic potential of interleukin-17 in inflammation and autoimmune diseases.Critical role of DNA methylation in the pathogenesis of systemic lupus erythematosus: new advances and future challenges.Facts and promises on lung biomarkers in interstitial lung diseases.The role of the acquired immune response in systemic sclerosis.CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.T and NK Cell Phenotypic Abnormalities in Systemic Sclerosis: a Cohort Study and a Comprehensive Literature Review.Treatment of Systemic Sclerosis-related Interstitial Lung Disease: A Review of Existing and Emerging Therapies.CD4(+)T-lymphocyte subsets in nonobese children with obstructive sleep apnea syndrome.Potential roles of interleukin-17A in the development of skin fibrosis in mice.IL-22 promotes fibroblast-mediated wound repair in the skin.Treg/Th17 cell balance and phytohaemagglutinin activation of T lymphocytes in peripheral blood of systemic sclerosis patients.IL-17 in the rheumatologist's line of sight.A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis.Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement.IL-17 and related cytokines involved in systemic sclerosis: Perspectives.Increased Th22 cells are independently associated with Th17 cells in type 1 diabetes.CXCL4 is a novel inducer of human Th17 cells and correlates with IL-17 and IL-22 in psoriatic arthritis.Th1- and Th17-polarized immune infiltrates in eosinophilic fasciitis-A potential marker for histopathologic distinction from morphea.Current perspectives on the role of CD8+ T cells in systemic sclerosis.Contribution of CD8+ T cells to inflammatory cytokine production in systemic sclerosis (SSc).

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Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease.

http://www.wikidata.org/entity/Q35840797

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Carlo Chizzolini

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Elisa Montanari

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Marie-Elise Truchetet

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Nicolò C Brembilla

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Yannick Allanore

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P2860

Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A

Circulating Th17, Th22, and Th1 cells are increased in psoriasis

Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

Chemokine: receptor structure, interactions, and antagonism

The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes.

Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent.

IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.

CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking.

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