Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism
about
The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancerMonoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven eventsTumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer.MiR-145 mediates zebrafish hepatic outgrowth through progranulin A signaling.Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice.Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline.Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).Progranulin as a prognostic biomarker for breast cancer recurrence in patients who had hormone receptor-positive tumors: a cohort study.Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice.Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells.Progranulin is a novel independent predictor of disease progression and overall survival in chronic lymphocytic leukemia.Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.Progranulin promotes colorectal cancer proliferation and angiogenesis through TNFR2/Akt and ERK signaling pathways.The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1.Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.Insights into the role of progranulin in immunity, infection, and inflammation.Interleukin-6-stimulated progranulin expression contributes to the malignancy of hepatocellular carcinoma cells by activating mTOR signaling.The challenge of cholangiocarcinoma: dissecting the molecular mechanisms of an insidious cancer.Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice.TGR5 signaling reduces neuroinflammation during hepatic encephalopathy.Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.Novel diagnostic and prognostic biomarkers in biliary tract cancer.Progranulin: a novel regulator of gastrointestinal cancer progression.The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation.New discovery rarely runs smooth: an update on progranulin/TNFR interactionsIL-6 is involved in malignancy and doxorubicin sensitivity of renal carcinoma cells.PGRN Suppresses Inflammation and Promotes Autophagy in Keratinocytes Through the Wnt/β-Catenin Signaling Pathway.Progranulin: A key player in autoimmune diseases.The role of progranulin in arthritis.Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.A solid-phase assay for studying direct binding of progranulin to TNFR and progranulin antagonism of TNF/TNFR interactions.Liver Fluke-Associated Biliary Tract Cancer.Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness.Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis.Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway.Tumor-related gene changes in immunosuppressive Syrian hamster cholangiocarcinoma.Progranulin as a predictive factor of response to chemotherapy in advanced biliary tract carcinoma.Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma.FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy.
P2860
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P2860
Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@ast
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@en
type
label
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@ast
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@en
prefLabel
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@ast
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@en
P2093
P2860
P50
P1433
P1476
Interleukin-6-driven progranul ...... by an Akt-dependent mechanism
@en
P2093
Brandon Cooper
Cheryl Galindo
Darijana Horvat
Gabriel Frampton
Hae Yong Pae
Matthew McMillin
Matthew Quinn
Sharon DeMorrow
P2860
P304
P356
10.1136/GUTJNL-2011-300643
P407
P577
2011-11-07T00:00:00Z